# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3362625 | Functional | Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assay | Mus musculus | 2 | ALA3351814 | cell-based format | Scientific Literature | |
2. | ALA3362626 | Functional | Agonist activity at mouse NMUR2 expressed in HEK293 cells by calcium mobilization assay | Mus musculus | 2 | ALA3351814 | cell-based format | Scientific Literature | |
3. | ALA4013732 | ADME | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assay | Homo sapiens | 27 | ALA4011647 | cell-based format | Scientific Literature | |
4. | ALA4013733 | Functional | Agonist activity at human NMUR2 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assay | Homo sapiens | 27 | ALA4011647 | cell-based format | Scientific Literature | |
5. | ALA4013734 | ADME | Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assay | Mus musculus | 27 | ALA4011647 | cell-based format | Scientific Literature | |
6. | ALA4013735 | Functional | Agonist activity at mouse NMUR2 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assay | Mus musculus | 27 | ALA4011647 | cell-based format | Scientific Literature | |
7. | ALA4047453 | Functional | Agonist activity at human NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLIPR assay | Homo sapiens | 20 | ALA4043242 | cell-based format | Scientific Literature | |
8. | ALA4047454 | Functional | Agonist activity at human NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLIPR assay | Homo sapiens | 20 | ALA4043242 | cell-based format | Scientific Literature | |
9. | ALA4047455 | Functional | Agonist activity at mouse NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLIPR assay | Mus musculus | 20 | ALA4043242 | cell-based format | Scientific Literature | |
10. | ALA4047456 | Functional | Agonist activity at mouse NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLIPR assay | Mus musculus | 20 | ALA4043242 | cell-based format | Scientific Literature | |
11. | ALA4146929 | Functional | Agonist activity at human NMUR1 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay | Homo sapiens | 38 | ALA4145476 | cell-based format | Scientific Literature | |
12. | ALA4146931 | Functional | Agonist activity at human NMUR2 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay | Homo sapiens | 41 | ALA4145476 | cell-based format | Scientific Literature | |
13. | ALA4146935 | Binding | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | Homo sapiens | 42 | ALA4145476 | cell-based format | Scientific Literature | |
14. | ALA4146936 | Binding | Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | Homo sapiens | 42 | ALA4145476 | cell-based format | Scientific Literature | |
15. | ALA4146937 | Binding | Selectivity ratio of IC50 for human NMUR2 expressed in HEK293 cell membranes to IC50 for NMUR1 expressed in HEK293 cell membranes | Homo sapiens | 36 | ALA4145476 | cell-based format | Scientific Literature | |
16. | ALA4146938 | ADME | Half life in human plasma at 112 uM by HPLC-UV/MS analysis | Homo sapiens | 8 | ALA4145476 | cell-free format | Scientific Literature | |
17. | ALA4149973 | Binding | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | Homo sapiens | 13 | ALA4145600 | cell-based format | Scientific Literature | |
18. | ALA4149974 | Binding | Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | Homo sapiens | 13 | ALA4145600 | cell-based format | Scientific Literature | |
19. | ALA4149975 | Functional | Agonist activity at human NMUR1 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintillation proximity assay | Homo sapiens | 13 | ALA4145600 | cell-based format | Scientific Literature | |
20. | ALA4149976 | Functional | Agonist activity at human NMUR2 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintillation proximity assay | Homo sapiens | 13 | ALA4145600 | cell-based format | Scientific Literature |