| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3385108 | B | Displacement of [3H]epibatidine from rat forebrain alpha2beta2 nAChR by competition binding assay | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 2. | ALA3385109 | B | Displacement of [3H]epibatidine from rat forebrain alpha2beta4 nAChR by competition binding assay | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 3. | ALA3385110 | B | Displacement of [3H]epibatidine from rat forebrain alpha3beta2 nAChR by competition binding assay | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 4. | ALA3385111 | B | Displacement of [3H]epibatidine from rat forebrain alpha3beta4 nAChR by competition binding assay | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 5. | ALA3385112 | B | Displacement of [3H]epibatidine from rat forebrain alpha4beta2 nAChR by competition binding assay | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 6. | ALA3385674 | B | Displacement of [3H]epibatidine from rat forebrain alpha4beta2* nAChR by competition binding assay | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 7. | ALA3385675 | B | Displacement of [3H]epibatidine from rat forebrain alpha4beta4 nAChR by competition binding assay | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 8. | ALA3385676 | B | Selectivity ratio of Ki for rat forebrain alpha3beta4 nAChR to rat forebrain alpha4beta2 nAChR | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 9. | ALA3385677 | B | Agonist activity at human alpha4beta2 nAChR expressed in SH-EP1 cells by [86Rb+] ion efflux assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA3385678 | B | Agonist activity at high-sensitivity human alpha4beta2 nAChR expressed in SH-EP1 cells by [86Rb+] ion efflux assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA3385679 | B | Agonist activity at low-sensitivity human alpha4beta2 nAChR expressed in SH-EP1 cells by [86Rb+] ion efflux assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA3385680 | B | Inactivation of human alpha4beta2 nAChR expressed in SH-EP1 cells by [86Rb+] ion efflux assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA3385681 | B | Inactivation of human alpha4beta2 nAChR expressed in SH-EP1 cells by [86Rb+] ion efflux assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA3385682 | B | Agonist activity at human alpha3beta4* expressed in SH-SY5Y cells at 10 uM by [86Rb+] ion efflux assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA3385683 | B | Agonist activity at human alpha1beta1gammadelta expressed in TE671/RD cells at 10 uM by [86Rb+] ion efflux assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 16. | ALA3385684 | A | Drug uptake in CD-1 mouse brain at 10 mg/kg, ip measured at 30 mins post dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3385685 | A | Drug uptake in CD-1 mouse brain at 10 mg/kg, ip measured at 120 mins post dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3385686 | A | Plasma concentration in CD-1 mouse at 10 mg/kg, ip measured at 30 mins post dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3385687 | A | Plasma concentration in CD-1 mouse at 10 mg/kg, ip measured at 120 mins post dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3389370 | A | Ratio of drug level in brain to plasma of CD-1 mouse at 10 mg/kg, ip measured at 30 mins post dose | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!