# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3383387 | B | Inhibition of NaV1.5 (unknown origin) | Homo sapiens | 1 | ALA3351317 | single protein format | Scientific Literature | |
2. | ALA3383388 | F | Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay | Homo sapiens | 22 | ALA3351317 | cell-based format | Scientific Literature | |
3. | ALA3383389 | F | Intrinsic activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay relative to oleoylethanolamide | Homo sapiens | 22 | ALA3351317 | cell-based format | Scientific Literature | |
4. | ALA3383390 | F | Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay | Mus musculus | 22 | ALA3351317 | cell-based format | Scientific Literature | |
5. | ALA3383391 | F | Intrinsic activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay relative to oleoylethanolamide | Mus musculus | 22 | ALA3351317 | cell-based format | Scientific Literature | |
6. | ALA3383392 | P | Distribution coefficient, log D between 1-octonol and aqueous phosphate buffer at pH 7.4 | 22 | ALA3351317 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA3383393 | P | Solubility in aqueous phosphate buffer at pH 7.4 after 24 hrs at 25 degC | 22 | ALA3351317 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA3383394 | B | Inhibition of human ERG by patch clamp based electrophysiology method | Homo sapiens | 22 | ALA3351317 | assay format | Scientific Literature | |
9. | ALA3383396 | A | Induction of seizures in rat brain hippocampal slices assessed as change in peak shape by electrophysiology method | Rattus norvegicus | 3 | ALA3351317 | tissue-based format | Scientific Literature | |
10. | ALA3383397 | A | Induction of seizures in rat brain hippocampal slices assessed as increase in population spikes at 1 uM to 30 uM by electrophysiology method | Rattus norvegicus | 1 | ALA3351317 | tissue-based format | Scientific Literature | |
11. | ALA3383398 | A | Induction of seizures in rat brain hippocampal slices assessed as change in peak area at 1 uM to 30 uM by electrophysiology method | Rattus norvegicus | 1 | ALA3351317 | tissue-based format | Scientific Literature | |
12. | ALA3383399 | T | Toxicity in mouse assessed as induction of tonic-clonic convulsions during 12 days study | Mus musculus | 2 | ALA3351317 | organism-based format | Scientific Literature | |
13. | ALA3383400 | A | fCmax in mouse during 12 days study | Mus musculus | 1 | ALA3351317 | organism-based format | Scientific Literature | |
14. | ALA3383972 | A | Inhibition of CYP1A2 (unknown origin) by high throughput fluorescence assay | Homo sapiens | 1 | ALA3351317 | single protein format | Scientific Literature | |
15. | ALA3383973 | A | Inhibition of CYP2C9 (unknown origin) by high throughput fluorescence assay | Homo sapiens | 1 | ALA3351317 | single protein format | Scientific Literature | |
16. | ALA3383974 | A | Inhibition of CYP2C19 (unknown origin) by high throughput fluorescence assay | Homo sapiens | 1 | ALA3351317 | single protein format | Scientific Literature | |
17. | ALA3383975 | A | Inhibition of CYP2D6 (unknown origin) by high throughput fluorescence assay | Homo sapiens | 1 | ALA3351317 | single protein format | Scientific Literature | |
18. | ALA3383976 | A | Inhibition of CYP3A4 (unknown origin) by high throughput fluorescence assay | Homo sapiens | 1 | ALA3351317 | single protein format | Scientific Literature | |
19. | ALA3383977 | A | Unbound fraction in mouse plasma | Mus musculus | 1 | ALA3351317 | cell-free format | Scientific Literature | |
20. | ALA3384634 | A | Unbound fraction in rat plasma | Rattus norvegicus | 1 | ALA3351317 | cell-free format | Scientific Literature |