# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3389592 | B | Inhibition of N-terminal His6-tagged mouse DNMT1 (731 to 1602 residues) expressed in Escherichia coli BL21 (DE3) incubated for 15 mins before addition of [3H]-SAM and poly(dI-dC).poly(dI-dC) by liquid scintillation counting based radioactive methylation assay | Mus musculus | 13 | assay format | Scientific Literature | ||
2. | ALA3390149 | B | Inhibition of N-terminal His6-tagged mouse DNMT1 (731 to 1602 residues) expressed in Escherichia coli BL21 (DE3) at 50 uM incubated for 15 mins before addition of [3H]-SAM and poly(dI-dC).poly(dI-dC) by liquid scintillation counting based radioactive methylation assay | Mus musculus | 19 | assay format | Scientific Literature | ||
3. | ALA4305408 | F | Otoprotective activity against gentamicin-induced outer hair cell death in CD-1 mouse cochlea at 20 uM after 48 hrs by TRITC-phalloidin staining-based microscopic analysis relative to control | Mus musculus | 18 | tissue-based format | Scientific Literature | ||
4. | ALA4305414 | T | Cytotoxicity against CD-1 mouse cochlea assessed as induction of cell damage at 20 uM in presence of gentamicin after 48 hrs by confocal microscopic analysis | Mus musculus | 5 | tissue-based format | Scientific Literature |