# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3390778 | B | Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assay | Homo sapiens | 25 | ALA3352760 | single protein format | Scientific Literature | |
2. | ALA3390779 | B | Inhibition of STAT3 (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assay | Homo sapiens | 1 | ALA3352760 | single protein format | Scientific Literature | |
3. | ALA3390780 | B | Binding affinity to full-length His-tagged STAT5B (unknown origin) by surface plasmon resonance assay | Homo sapiens | 1 | ALA3352760 | single protein format | Scientific Literature | |
4. | ALA3390781 | B | Binding affinity to full-length His-tagged STAT3 (unknown origin) by surface plasmon resonance assay | Homo sapiens | 1 | ALA3352760 | single protein format | Scientific Literature | |
5. | ALA3390782 | B | Inhibition of JAK1/2 (unknown origin) | Homo sapiens | 1 | ALA3352760 | protein complex format | Scientific Literature | |
6. | ALA3390783 | B | Inhibition of ABL (unknown origin) | Homo sapiens | 1 | ALA3352760 | single protein format | Scientific Literature | |
7. | ALA3390784 | B | Inhibition of FLT3 (unknown origin) | Homo sapiens | 1 | ALA3352760 | single protein format | Scientific Literature | |
8. | ALA3381652 | F | Cytotoxicity against human K562 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Blue assay | Homo sapiens | 8 | ALA3352760 | cell-based format | Scientific Literature | |
9. | ALA3381653 | F | Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
10. | ALA3381654 | B | Inhibition of STAT5 phosphorylation at Y694 residue in human K562 cells after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
11. | ALA3381655 | B | Inhibition of STAT5 phosphorylation at Y694 residue in human K562 cells at 10 uM after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
12. | ALA3381656 | F | Effect on total STAT5 level in human K562 cells at 15 uM after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
13. | ALA3381657 | F | Induction of apoptosis in human K562 cells assessed as PARP1 cleavage at 15 uM after 24 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
14. | ALA3381658 | F | Induction of apoptosis in human K562 cells assessed as caspase3 activation at 15 uM after 24 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
15. | ALA3381659 | B | Inhibition of STAT3 phosphorylation in human MDA-MB-231 cells at 15 uM after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
16. | ALA3381660 | F | Effect on total STAT5 level in human MDA-MB-231 cells at 15 uM after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
17. | ALA3381661 | F | Effect on total STAT3 level in human MDA-MB-231 cells at 15 uM after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
18. | ALA3381662 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
19. | ALA3381663 | F | Selectivity ratio of IC50 for human MDA-MB-231 cells to IC50 for human K562 cells | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature | |
20. | ALA3381664 | B | Inhibition of STAT5 phosphorylation at Y694 residue in human K562 cells assessed as decreases in MYC expression after 5 hrs by Western blotting | Homo sapiens | 1 | ALA3352760 | cell-based format | Scientific Literature |