# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3383863 | B | Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP at 10 uM after 20 mins by scintillation proximity assay | Homo sapiens | 63 | ALA3352280 | single protein format | Scientific Literature | |
2. | ALA3383864 | B | Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay | Homo sapiens | 37 | ALA3352280 | single protein format | Scientific Literature | |
3. | ALA3383865 | B | Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP at 10 uM after 20 mins by scintillation proximity assay | Homo sapiens | 8 | ALA3352280 | single protein format | Scientific Literature | |
4. | ALA3383866 | B | Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay | Homo sapiens | 6 | ALA3352280 | single protein format | Scientific Literature | |
5. | ALA3383867 | B | Inhibition of human recombinant PDE3A assessed as inhibition of hydrolysis of [3H]cAMP at 10 uM after 20 mins by scintillation proximity assay | Homo sapiens | 11 | ALA3352280 | single protein format | Scientific Literature | |
6. | ALA3383868 | B | Inhibition of human recombinant PDE4D3 assessed at 10 uM after 60 mins by IMAP fluorescence polarization assay | Homo sapiens | 9 | ALA3352280 | single protein format | Scientific Literature | |
7. | ALA3383870 | B | Inhibition of human recombinant PDE4B2 assessed at 10 uM after 60 mins by IMAP fluorescence polarization assay | Homo sapiens | 9 | ALA3352280 | single protein format | Scientific Literature | |
8. | ALA3383878 | F | Cytoprotective activity against 6-OHDA-induced death of human SH-SY5Y cells pretreated for 1 hr at 10 uM measured 16 hrs post 6-OHDA challenge by MTT assay | Homo sapiens | 8 | ALA3352280 | cell-based format | Scientific Literature | |
9. | ALA3383881 | F | Inhibition of LPS-induced NO production in rat astrocytes treated for 1 hr at 10 uM before LPS challenge measured after 24 hrs by Griess assay | Rattus norvegicus | 8 | ALA3352280 | cell-based format | Scientific Literature | |
10. | ALA3383882 | F | Inhibition of LPS-induced NO production in rat microglia treated for 1 hr at 10 uM before LPS challenge measured after 24 hrs by Griess assay | Rattus norvegicus | 8 | ALA3352280 | assay format | Scientific Literature | |
11. | ALA3383883 | A | Permeability of the compound at pH 7.4 by PAMPA | 7 | ALA3352280 | assay format | Scientific Literature |
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