# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3374592 | B | Inhibition of HIF-1alpha in human HCT116 cells incubated for 12 hrs under hypoxic conditions by Western blotting and HRE-luciferase reporter assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
2. | ALA3374593 | B | Inhibition of MDH2 (unknown origin) pre-incubated for 1 hr followed by malate and NAD+ addition | Homo sapiens | 9 | single protein format | Scientific Literature | ||
3. | ALA3374594 | B | Binding affinity to human recombinant MDH2 at 10 uM under UV irradiation by SDS-PAGE based photo-affinity labeling method | Homo sapiens | 6 | single protein format | Scientific Literature | ||
4. | ALA3374595 | F | Reduction in oxygen consumption in human HCT116 cells at 20 uM incubated for 3 hrs by thermoregulated controlled circulating system method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3374596 | F | Reduction in ATP production in human HCT116 cells at 10 uM by luciferase based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3374597 | B | Inhibition of MDH2 in human HCT116 cells assessed as AMPK activation at 10 uM by immunoblot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA3374598 | B | Inhibition of MDH2 in human HCT116 cells assessed as reduction in ACC phosphorylation at 10 uM by immunoblot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA3374599 | B | Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plot | Homo sapiens | 2 | single protein format | Scientific Literature |