# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3380138 | F | Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay | Homo sapiens | 11 | ALA3352004 | assay format | Scientific Literature | |
2. | ALA3380139 | F | Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay relative to S1P | Homo sapiens | 11 | ALA3352004 | assay format | Scientific Literature | |
3. | ALA3380140 | B | Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay | Homo sapiens | 5 | ALA3352004 | single protein format | Scientific Literature | |
4. | ALA3380141 | B | Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay relative to S1P | Homo sapiens | 5 | ALA3352004 | single protein format | Scientific Literature | |
5. | ALA3380142 | B | Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay | Homo sapiens | 5 | ALA3352004 | single protein format | Scientific Literature | |
6. | ALA3380143 | B | Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay | Homo sapiens | 5 | ALA3352004 | single protein format | Scientific Literature | |
7. | ALA3380144 | B | Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay | Homo sapiens | 5 | ALA3352004 | single protein format | Scientific Literature | |
8. | ALA3380145 | B | Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay relative to S1P | Homo sapiens | 3 | ALA3352004 | single protein format | Scientific Literature | |
9. | ALA3380146 | B | Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay | Homo sapiens | 5 | ALA3352004 | single protein format | Scientific Literature | |
10. | ALA3380147 | B | Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay relative to S1P | Homo sapiens | 4 | ALA3352004 | single protein format | Scientific Literature | |
11. | ALA3380148 | A | Systemic clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
12. | ALA3380149 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
13. | ALA3380150 | A | Cmax in Sprague-Dawley rat at 1 mg/kg, po | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
14. | ALA3380151 | A | Tmax in Sprague-Dawley rat at 1 mg/kg, po | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
15. | ALA3380152 | A | AUC (0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv or at 1 mg/kg, po | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
16. | ALA3380153 | A | Elimination half life in Sprague-Dawley rat at 1 mg/kg, po | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
17. | ALA3380154 | A | Oral bioavailability in Sprague-Dawley rat at 1 mg/kg | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
18. | ALA3380155 | A | Ratio of drug level in brain to plasma in Sprague-Dawley rat | Rattus norvegicus | 4 | ALA3352004 | cell-free format | Scientific Literature | |
19. | ALA3380156 | F | Reduction in lymphocyte count in Sprague-Dawley rat | Rattus norvegicus | 4 | ALA3352004 | organism-based format | Scientific Literature | |
20. | ALA3380157 | F | Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assay | Mus musculus | 2 | ALA3352004 | assay format | Scientific Literature |