| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3383761 | B | Inhibition of PDE9A2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 2. | ALA3383762 | B | Inhibition of PDE1B2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA3383763 | B | Inhibition of PDE4D2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 4. | ALA3383764 | B | Inhibition of PDE5A1 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA3383765 | B | Inhibition of PDE7A1 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA3383766 | B | Inhibition of PDE8A1 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 7. | ALA3383767 | B | Inhibition of PDE10A2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 8. | ALA3383768 | B | Inhibition of PDE2A3 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA3383769 | B | Inhibition of PDE3A catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA3383770 | B | Selectivity ratio of IC50 for PDE1B2 catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 11. | ALA3383771 | B | Selectivity ratio of IC50 for PDE4D2 catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 12. | ALA3383772 | B | Selectivity ratio of IC50 for PDE5A1 catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 13. | ALA3383773 | B | Selectivity ratio of IC50 for PDE7A1 catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA3384347 | B | Selectivity ratio of IC50 for PDE10A2 catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 15. | ALA3384348 | B | Selectivity ratio of IC50 for PDE2A3 catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA3384349 | B | Selectivity ratio of IC50 for PDE3A catalytic domain (unknown origin) to IC50 for PDE9A2 catalytic domain (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA3384350 | A | Plasma protein binding in human at 1 to 5 uM after 4 hrs by LC/MS/MS analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 18. | ALA3384351 | A | Solubility of the compound in simulated gastric fluid at pH 1.4 after 24 to 48 hrs by HPLC analysis | 3 | tissue-based format | Scientific Literature | |||
| 19. | ALA3384352 | A | Solubility of the compound in simulated intestinal fluid at pH 6.8 after 24 to 48 hrs by HPLC analysis | 3 | assay format | Scientific Literature | |||
| 20. | ALA3384353 | A | Half life in CD-1 mouse liver microsomes at 0.75 uM incubated for 5 mins prior to NADPH addition measured after 30 mins by LC/MS/MS analysis | Mus musculus | 4 | assay format | Scientific Literature |
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