# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3377012 | B | Binding affinity to LXRalpha-RXRalpha heterodimer (unknown origin) expressed in insect cells by scintillation proximity assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
2. | ALA3377013 | B | Binding affinity to LXRbeta-RXRalpha heterodimer (unknown origin) expressed in insect cells by scintillation proximity assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
3. | ALA3377014 | B | Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
4. | ALA3377015 | B | Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
5. | ALA3377016 | B | Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay relative to 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
6. | ALA3377017 | B | Transactivation of LXR (unknown origin) expressed in human HeLa cells by ABCA1 LXREx3 reporter assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA3377018 | B | Transactivation of LXR (unknown origin) expressed in human HeLa cells by ABCA1 LXREx3 reporter assay relative to 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
8. | ALA3377028 | A | Elevation of hepatic triglyceride in C57BL/6 mouse at 30 mg/kg for 7 days measured 24 hrs post last dose relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
9. | ALA3377031 | A | Induction of SREBP1c mRNA in C57BL/6 mouse liver at 30 mg/kg for 7 days measured 24 hrs post last dose relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
10. | ALA3378884 | B | Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay relative to 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 17 | cell-based format | Scientific Literature |