# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3377012 | B | Binding affinity to LXRalpha-RXRalpha heterodimer (unknown origin) expressed in insect cells by scintillation proximity assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
2. | ALA3377013 | B | Binding affinity to LXRbeta-RXRalpha heterodimer (unknown origin) expressed in insect cells by scintillation proximity assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
3. | ALA3377014 | B | Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
4. | ALA3377015 | B | Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
5. | ALA3377017 | B | Transactivation of LXR (unknown origin) expressed in human HeLa cells by ABCA1 LXREx3 reporter assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
6. | ALA3377018 | B | Transactivation of LXR (unknown origin) expressed in human HeLa cells by ABCA1 LXREx3 reporter assay relative to 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA3377019 | B | Transactivation of LXR in human whole blood assessed as induction of ABCA1 after 4 hrs by SYBR-Green quantitative PCR analysis | Homo sapiens | 6 | protein format | Scientific Literature | ||
8. | ALA3377020 | A | Plasma concentration in mouse at 30 mg/kg, po measured at 4 hrs post dose | Mus musculus | 9 | organism-based format | Scientific Literature | ||
9. | ALA3377021 | A | Plasma concentration in mouse at 30 mg/kg, po measured at 24 hrs post dose | Mus musculus | 9 | organism-based format | Scientific Literature | ||
10. | ALA3377022 | A | Drug uptake in mouse liver at 30 mg/kg, po measured at 24 hrs post dose | Mus musculus | 8 | organism-based format | Scientific Literature | ||
11. | ALA3378884 | B | Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay relative to 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
12. | ALA3378885 | B | Transactivation of LXR in human whole blood assessed as induction of ABCA1 after 4 hrs by SYBR-Green quantitative PCR analysis relative to 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 6 | protein format | Scientific Literature |