# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3259253 | Binding | Inhibition of HMG-coA reductase in CD rat liver microsomal-cytosol fraction assessed as inhibition of total lipid synthesis using [2-14C]acetate as substrate after 90 mins by scintillation counting analysis | Rattus norvegicus | 15 | ALA3244254 | assay format | Scientific Literature | |
2. | ALA3259254 | Binding | Inhibition of HMG-coA reductase in CD rat liver microsomal-cytosol fraction assessed as inhibition of nonsaponifiable lipid synthesis using [2-14C]acetate as substrate after 90 mins by scintillation counting analysis | Rattus norvegicus | 15 | ALA3244254 | assay format | Scientific Literature | |
3. | ALA3259255 | Binding | Inhibition of HMG-coA reductase in CD rat liver microsomal-cytosol fraction assessed as inhibition of fatty acid synthesis using [2-14C]acetate as substrate after 90 mins by scintillation counting analysis | Rattus norvegicus | 15 | ALA3244254 | assay format | Scientific Literature | |
4. | ALA3256510 | Functional | Hypolipidemic activity in intact normal CD rat assessed as reduction in serum cholesterol level at 0.51 mmol/kg/day administered through diet for 5 days measured on day 6 | Rattus norvegicus | 1 | ALA3244254 | organism-based format | Scientific Literature | |
5. | ALA3256511 | Functional | Hypolipidemic activity in intact normal CD rat assessed as reduction in serum triglyceride level at 0.51 mmol/kg/day administered through diet for 5 days measured on day 6 | Rattus norvegicus | 1 | ALA3244254 | organism-based format | Scientific Literature |