| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3395438 | B | Inhibition of PRL-3-mediated cell migration in human HEK293 cells expressing PRL-3 (unknown origin) assessed as reduction of cell migrated at 35 uM after 0 to 20 hrs by wound healing assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3395439 | B | Inhibition of PRL-3-mediated cell migration in human HEK293 cells expressing PRL-3 (unknown origin) assessed as reduction of cell migrated at 25 uM after 0 to 20 hrs by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3395440 | B | Inhibition of PRL-3-mediated cell migration in human HEK293 cells expressing PRL-3 (unknown origin) assessed as reduction of cell migrated at 12 uM after 0 to 20 hrs by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3395441 | B | Inhibition of PRL-3-mediated cell migration in human HEK293 cells expressing PRL-3 (unknown origin) assessed as reduction of cell migrated treated for 0 to 20 hrs by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3395442 | B | Inhibition of PRL-2-mediated cell migration in human HEK293 cells expressing PRL-2 (unknown origin) assessed as reduction of cell migrated at 50 uM after 0 to 20 hrs by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3395443 | B | Inhibition of PRL-1-mediated cell migration in human HEK293 cells expressing PRL-1 (unknown origin) assessed as reduction of cell migrated at 50 uM after 0 to 20 hrs by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3395571 | F | Effect on cell proliferation of human HEK293 cells expressing human PRL-3 at 50 uM after 1 to 9 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3395572 | A | Effect on cell proliferation of human HEK293 cells expressing empty vector at 50 uM after 1 to 9 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3395575 | A | Drug localization in plasma membrane of HEK293 cells transfected with mKate-PRL-3 at 50 uM incubated for 30 mins by confocal microscopy | Homo sapiens | 2 | cell membrane format | Scientific Literature | ||
| 10. | ALA3395576 | A | Drug localization in inner membrane compartments of HEK293 cells transfected with mKate-PRL-3 at 50 uM incubated for 30 mins by confocal microscopy | Homo sapiens | 2 | cell membrane format | Scientific Literature | ||
| 11. | ALA3395080 | B | Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 12. | ALA3395081 | B | Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 13. | ALA3395082 | B | Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 14. | ALA3395083 | P | Solubility in buffer assessed as light scattering | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA3395084 | B | Selectivity index, ratio of IC50 for PTP1B (unknown origin) to IC50 for PRL3 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 16. | ALA3395085 | B | Selectivity index, ratio of IC50 for TCPTP (unknown origin) to IC50 for PRL3 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 17. | ALA3395086 | A | Cytotoxicity against human HEK293 cells expressing human PRL-3 at 50 to 75 uM after 16 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA3395087 | B | Selectivity index, ratio of IC50 for VHR (unknown origin) to IC50 for PRL3 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 19. | ALA3395088 | A | Cytotoxicity against human HEK293 cells expressing human PRL-1 at 50 to 75 uM after 16 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 20. | ALA3395089 | A | Cytotoxicity against human HEK293 cells expressing human PRL-2 at 50 to 75 uM after 16 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature |
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