# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3396210 | A | Cytotoxicity against human HuH7 cells assessed as inhibition of cell viability after 3 days by CellTiter 96 assay | Homo sapiens | 25 | ALA3392986 | cell-based format | Scientific Literature | |
2. | ALA3396292 | F | Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by luciferase reporter gene assay | Hepacivirus hominis | 25 | ALA3392986 | cell-based format | Scientific Literature | |
3. | ALA3396295 | A | Therapeutic index, ratio of CC50 for human HuH7 cells to EC50 for HCV genotype 1b infected in human Huh7 cells | 24 | ALA3392986 | cell-based format | Scientific Literature | ||
4. | ALA3755708 | F | Antiviral activity against HCV assessed as reduction of viral replicon RNA level by RT-qPCR analysis | Hepacivirus hominis | 2 | ALA3751715 | organism-based format | Scientific Literature | |
5. | ALA3755709 | B | Inhibition of full length C-terminal GST-tagged human HDAC1 expressed in Sf9 cells using (Arg-His-Lys-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | cell-based format | Scientific Literature | |
6. | ALA3755710 | B | Inhibition of full length C-terminal His-tagged human HDAC2 expressed in Sf9 cells using (Arg-His-Lys-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | cell-based format | Scientific Literature | |
7. | ALA3755711 | B | Inhibition of full length C-terminal His-tagged human HDAC3 expressed in baculovirus expression system using (Arg-His-Lys-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
8. | ALA3755712 | B | Inhibition of N-terminal GST-tagged human HDAC4 expressed in baculovirus expression system using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
9. | ALA3755713 | B | Inhibition of full length N-terminal GST-tagged human HDAC5 expressed in Sf9 cells using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | cell-based format | Scientific Literature | |
10. | ALA3755714 | B | Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in Sf9 cells using (Arg-His-Lys-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | cell-based format | Scientific Literature | |
11. | ALA3755715 | B | Inhibition of N-terminal GST-tagged human HDAC7 expressed in baculovirus expression system using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
12. | ALA3755716 | B | Inhibition of full length human HDAC8 expressed in Escherichia coli using (Arg-His-Lys(Ac)-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
13. | ALA3755717 | B | Inhibition of C-terminal His-tagged human HDAC9 expressed in baculovirus expression system using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
14. | ALA3755718 | B | Inhibition of N-terminal GST-tagged human HDAC10 expressed in Sf9 cells using (Arg-His-Lys-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | cell-based format | Scientific Literature | |
15. | ALA3755719 | B | Inhibition of N-terminal GST-tagged human HDAC11 expressed in baculovirus expression system using (Arg-His-Lys-Lys(Ac)) as substrate by plate reader analysis | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
16. | ALA3755720 | B | Inhibition of human recombinant MMP1 expressed in Escherichia coli using (5-FAM/QXLTM) FRET peptide as substrate | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
17. | ALA3755721 | B | Inhibition of human recombinant MMP1 expressed in yeast using (5-FAM/QXLTM) FRET peptide as substrate | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
18. | ALA3755722 | B | Inhibition of human recombinant MMP3 expressed in Escherichia coli using (5-FAM/QXLTM) FRET peptide as substrate | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature | |
19. | ALA3755723 | B | Inhibition of recombinant HCV genotype 1b NS5B Cdelta55 RNA dependent RNA polymerase at 10 uM incubated for 3 hrs using Oligo-U12 primer, UTP and Poly(A) template by scintillation proximity assay | Hepatitis C virus subtype 1b | 1 | ALA3751715 | assay format | Scientific Literature | |
20. | ALA3755724 | B | Inhibition of human recombinant MMP7 expressed in Escherichia coli using (5-FAM/QXLTM) FRET peptide as substrate | Homo sapiens | 1 | ALA3751715 | assay format | Scientific Literature |