# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3396589 | F | Antifungal activity against Histoplasma capsulatum G217B ATCC 26032 assessed as inhibition of visible growth after 5 days | Histoplasma capsulatum G217B | 67 | ALA3393037 | assay format | Scientific Literature | |
2. | ALA3396590 | F | Antifungal activity against Cryptococcus neoformans MATalpha serotype A strain H99 assessed as inhibition of visible growth after 5 days | Cryptococcus neoformans | 65 | ALA3393037 | organism-based format | Scientific Literature | |
3. | ALA3396591 | A | Cytotoxicity against human HepG2 cells after 72 hrs by crystal violet staining method | Homo sapiens | 55 | ALA3393037 | cell-based format | Scientific Literature | |
4. | ALA3396592 | U | Selectivity index, ratio of MIC50 for Histoplasma capsulatum strain G217B ATCC 26032 to MIC50 for human HepG2 cells | 53 | ALA3393037 | cell-based format | Scientific Literature | ||
5. | ALA4222852 | F | Antifungal activity against Histoplasma capsulatum G217B ATCC 26032 at pH 7 measured over 5 days | Histoplasma capsulatum | 35 | ALA4219175 | organism-based format | Scientific Literature | |
6. | ALA4222853 | F | Antifungal activity against wild type fluconazole-sensitive Cryptococcus neoformans serotype A H99 at pH 7 measured over 4 days | Cryptococcus neoformans | 36 | ALA4219175 | organism-based format | Scientific Literature | |
7. | ALA4222854 | A | Cytotoxicity against mouse P388D1 cells assessed as reduction in cell viability after 72 hrs by resazurin-based fluorescence assay | Mus musculus | 35 | ALA4219175 | cell-based format | Scientific Literature | |
8. | ALA4222855 | T | Therapeutic index, ratio of IC50 for mouse P388D1 cells to IC50 for Histoplasma capsulatum G217B ATCC 26032 | 35 | ALA4219175 | assay format | Scientific Literature | ||
9. | ALA4222856 | T | Therapeutic index, ratio of IC50 for mouse P388D1 cells to IC50 for wild type Cryptococcus neoformans serotype A H99 | 35 | ALA4219175 | assay format | Scientific Literature |