# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3396816 | B | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 29 | microsome format | Scientific Literature | ||
2. | ALA3396817 | B | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
3. | ALA3396818 | A | Metabolic stability in rat liver microsome assessed as compound remaining after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 29 | microsome format | Scientific Literature | ||
4. | ALA3396819 | F | Antiobesity activity in Lewis rat DI model assessed as reduction in plasma C16:1/C16:0 TG desaturation index at 5 mg/kg, po after 4 hrs | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
5. | ALA3396820 | A | Permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
6. | ALA3396832 | T | Toxicity in female Sprague-Dawley rat assessed as induction of red eye at 100 mg/kg, po once daily for 10 consecutive days | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
7. | ALA3396835 | A | Permeability from basolateral to apical side side in human Caco2 cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
8. | ALA3396836 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM by thin layer chromatography method | Rattus norvegicus | 23 | microsome format | Scientific Literature | ||
9. | ALA3396837 | B | Inhibition of delta6 desaturase in Sprague-Dawley rat liver microsome using cis,cis-9,12-octadecadienoic acid substrate at 10 uM by thin layer chromatography method | Rattus norvegicus | 23 | microsome format | Scientific Literature | ||
10. | ALA3396839 | T | Toxicity in female Sprague-Dawley rat assessed as induction of dry skin at 100 mg/kg, po once daily for 10 consecutive days | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
11. | ALA3396840 | T | Toxicity in female Sprague-Dawley rat assessed as induction of hair loss at 100 mg/kg, po once daily for 10 consecutive days | Rattus norvegicus | 8 | organism-based format | Scientific Literature |