| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3396816 | B | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 29 | microsome format | Scientific Literature | ||
| 2. | ALA3396817 | B | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 3. | ALA3396818 | A | Metabolic stability in rat liver microsome assessed as compound remaining after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 29 | microsome format | Scientific Literature | ||
| 4. | ALA3396819 | F | Antiobesity activity in Lewis rat DI model assessed as reduction in plasma C16:1/C16:0 TG desaturation index at 5 mg/kg, po after 4 hrs | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
| 5. | ALA3396820 | A | Permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 6. | ALA3396821 | A | Clearance in Lewis rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3396822 | A | Half life in Lewis rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA3396823 | A | Cmax in Lewis rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3396824 | A | Volume of distribution at steady state in Lewis rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3396825 | A | Terminal half life in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3396826 | A | AUC (0 to 24 hrs) in Lewis rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3396827 | A | Cmax in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3396828 | A | Tmax in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3396829 | A | AUC (0 to 24 hrs) at steady state in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA3396830 | A | Oral bioavailability in Lewis rat at 5 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA3396832 | T | Toxicity in female Sprague-Dawley rat assessed as induction of red eye at 100 mg/kg, po once daily for 10 consecutive days | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 17. | ALA3396833 | A | AUC (0 to 24 hrs) in female Sprague-Dawley rat at 100 mg/kg, po once daily for 10 consecutive days measured on day 11 | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3396834 | F | Antiobesity activity in po dosed Lewis rat DI model assessed as reduction in plasma C16:1/C16:0 TG desaturation index after 4 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3396835 | A | Permeability from basolateral to apical side side in human Caco2 cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 20. | ALA3396836 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM by thin layer chromatography method | Rattus norvegicus | 23 | microsome format | Scientific Literature |
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