# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3399801 | B | Inhibition of CYP11B2 in human V79MZ cells using [3H]-11-deoxycorticosterone as substrate at 500 nM incubated for 1 hr prior to substrate addition measured after 45 mins by HPLC analysis | Homo sapiens | 15 | ALA3396957 | cell-based format | Scientific Literature | |
2. | ALA3399802 | B | Inhibition of CYP11B2 in human V79MZ cells using [3H]-11-deoxycorticosterone as substrate incubated for 1 hr prior to substrate addition measured after 45 mins by HPLC analysis | Homo sapiens | 19 | ALA3396957 | cell-based format | Scientific Literature | |
3. | ALA3399803 | B | Inhibition of CYP11B1 in human V79MZ cells using [3H]-11-deoxycorticosterone as substrate incubated for 1 hr prior to substrate addition measured after 25 mins by HPLC analysis | Homo sapiens | 19 | ALA3396957 | cell-based format | Scientific Literature | |
4. | ALA3399804 | B | Selectivity factor, ratio of IC50 for CYP11B1 in human V79MZ cells to IC50 for CYP11B2 in human V79MZ cells | Homo sapiens | 19 | ALA3396957 | cell-based format | Scientific Literature | |
5. | ALA3399806 | B | Inhibition of human recombinant CYP17 expressed in Escherichia coli using progesterone as substrate at 2 uM | Homo sapiens | 7 | ALA3396957 | assay format | Scientific Literature | |
6. | ALA3399807 | B | Inhibition of human recombinant CYP19 using [1beta-3H]androstenedione as substrate at 500 nM | Homo sapiens | 7 | ALA3396957 | single protein format | Scientific Literature | |
7. | ALA3399808 | B | Inhibition of rat CYP11B2 using [3H]-11-deoxycorticosterone as substrate at 2 uM incubated for 1 hr prior to substrate addition measured after 7 hrs by HPLC analysis | Rattus norvegicus | 5 | ALA3396957 | single protein format | Scientific Literature |