# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3398864 | F | Prevention of right ventricular weight increase in rat model of monocrotaline-induced pulmonary arterial hypertension at 30 mg/kg, sc administered twice daily for 21 days relative to sham animal (Rvb = 19 no unit) | Rattus norvegicus | 2 | ALA3397017 | organism-based format | Scientific Literature | |
2. | ALA3398865 | F | Prevention of right ventricular weight increase in rat model of monocrotaline-induced pulmonary arterial hypertension at 10 mg/kg, sc administered twice daily for 21 days relative to sham animal (Rvb = 19 no unit) | Rattus norvegicus | 2 | ALA3397017 | organism-based format | Scientific Literature | |
3. | ALA3398868 | F | Agonist activity at human recombinant DP1 receptor by cAMP assay | Homo sapiens | 2 | ALA3397017 | single protein format | Scientific Literature | |
4. | ALA3398870 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | ALA3397017 | organism-based format | Scientific Literature | |
5. | ALA3398871 | A | Half life in iv dosed rat | Rattus norvegicus | 1 | ALA3397017 | organism-based format | Scientific Literature | |
6. | ALA3399046 | F | Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assay | Homo sapiens | 32 | ALA3397017 | cell-based format | Scientific Literature | |
7. | ALA3399047 | F | Intrinsic activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assay relative to 1 uM iloprost | Homo sapiens | 32 | ALA3397017 | cell-based format | Scientific Literature | |
8. | ALA3399048 | F | Agonist activity at rat recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assay | Rattus norvegicus | 32 | ALA3397017 | cell-based format | Scientific Literature | |
9. | ALA3399049 | F | Intrinsic activity at rat recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assay relative to 1 uM iloprost | Rattus norvegicus | 32 | ALA3397017 | cell-based format | Scientific Literature | |
10. | ALA3399050 | B | Agonist activity at human recombinant DP1 receptor expressed in melanophores assessed as induction of pigment redistribution incubated for 90 mins | Homo sapiens | 32 | ALA3397017 | assay format | Scientific Literature | |
11. | ALA3399051 | B | Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation | Homo sapiens | 16 | ALA3397017 | assay format | Scientific Literature |