| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3398883 | P | Dissociation constant, pKa of the compound | 1 | ALA3397011 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA3398884 | F | Antimicrobial activity against isoniazid and rifampin resistant Mycobacterium tuberculosis after 21 days at 37 degC by agar dilution drug susceptibility assay | Mycobacterium tuberculosis | 6 | ALA3397011 | organism-based format | Scientific Literature | |
| 3. | ALA3398885 | F | Antimicrobial activity against isoniazid and rifampin resistant Mycobacterium tuberculosis after 21 days at 37 degC in presence of PA-824 by agar dilution drug susceptibility assay | Mycobacterium tuberculosis | 1 | ALA3397011 | organism-based format | Scientific Literature | |
| 4. | ALA3398887 | F | Antimicrobial activity against isoniazid and rifampin resistant Mycobacterium tuberculosis assessed as ratio of MIC combination/MIC compound alone after 21 days at 37 degC in presence of PA-824 by agar dilution drug susceptibility assay | Mycobacterium tuberculosis | 1 | ALA3397011 | organism-based format | Scientific Literature | |
| 5. | ALA3398889 | F | Antimicrobial activity against isoniazid and rifampin resistant Mycobacterium tuberculosis assessed as reduction in colony forming unit after 21 days at 37 degC in presence of PA-824 by agar dilution drug susceptibility assay | Mycobacterium tuberculosis | 1 | ALA3397011 | organism-based format | Scientific Literature | |
| 6. | ALA3398891 | A | Toxicity against macrophages (unknown origin) assessed cell viability at 4 times MIC level after 7 days by MTT assay | Not specified | 2 | ALA3397011 | cell-based format | Scientific Literature | |
| 7. | ALA3398962 | A | Half life in pooled mixed-gender human liver microsomes at 50 uM in presence of NADPH pre-incubated for 3 mins before NADPH addition followed by incubation for 60 mins by reversed-phase HPLC method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 8. | ALA3398963 | A | Inhibition of CYP3A4 in pooled mixed-gender human liver microsomes using testosterone substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 9. | ALA3398964 | A | Inhibition of CYP3A4 in pooled mixed-gender human liver microsomes using triazolam substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 10. | ALA3398965 | A | Inhibition of CYP3D6 in pooled mixed-gender human liver microsomes using dextromethorphan substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 11. | ALA3398966 | A | Inhibition of CYP3A4 in pooled mixed-gender human liver microsomes at <25 uM using testosterone substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 12. | ALA3398967 | A | Inhibition of CYP3A4 in pooled mixed-gender human liver microsomes at <25 uM using triazolam substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 13. | ALA3398968 | A | Inhibition of CYP3D6 in pooled mixed-gender human liver microsomes at <25 uM using dextromethorphan substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 14. | ALA3398969 | A | Activation of CYP3A4 in pooled mixed-gender human liver microsomes using testosterone substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 15. | ALA3398970 | A | Activation of CYP3A4 in pooled mixed-gender human liver microsomes using triazolam substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 16. | ALA3398971 | A | Activation of CYP3D6 in pooled mixed-gender human liver microsomes using dextromethorphan substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV detection method | Homo sapiens | 1 | ALA3397011 | assay format | Scientific Literature | |
| 17. | ALA3398972 | A | Drug metabolism assessed as UGT1A1-mediated compound glucuronidation in pooled mixed-gender human liver microsomes at 50 uM preincubated at 37 degC for 3 mins before UDPGA addition by HPLC method | Homo sapiens | 2 | ALA3397011 | assay format | Scientific Literature | |
| 18. | ALA3398973 | A | Drug metabolism assessed as UGT1A4-mediated compound glucuronidation in pooled mixed-gender human liver microsomes at 50 uM preincubated at 37 degC for 3 mins before UDPGA addition by HPLC method | Homo sapiens | 2 | ALA3397011 | assay format | Scientific Literature | |
| 19. | ALA3398974 | A | Drug metabolism assessed as UGT1A6-mediated compound glucuronidation in pooled mixed-gender human liver microsomes at 50 uM preincubated at 37 degC for 3 mins before UDPGA addition by HPLC method | Homo sapiens | 2 | ALA3397011 | assay format | Scientific Literature | |
| 20. | ALA3398975 | A | Drug metabolism assessed as UGT1A9-mediated compound glucuronidation in pooled mixed-gender human liver microsomes at 50 uM preincubated at 37 degC for 3 mins before UDPGA addition by HPLC method | Homo sapiens | 2 | ALA3397011 | assay format | Scientific Literature |
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