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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3399217 F Antagonist activity against human OX1 receptor expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated for 30 mins by Fluo-4 AM dye based fluorescence assay Homo sapiens 18 ALA3397044 cell-based format Scientific Literature 2. ALA3399218 F Antagonist activity against human OX2 receptor expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated for 30 mins by Fluo-4 AM dye based fluorescence assay Homo sapiens 18 ALA3397044 cell-based format Scientific Literature 3. ALA3399219 A Drug metabolism in human liver microsomes at 5 uM after 15 mins Homo sapiens 6 ALA3397044 assay format Scientific Literature 4. ALA3399220 A Volume of distribution in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 2 ALA3397044 organism-based format Scientific Literature 5. ALA3399221 A Clearance in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 2 ALA3397044 organism-based format Scientific Literature 6. ALA3399222 A Half life in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 2 ALA3397044 organism-based format Scientific Literature 7. ALA3399358 A Tmax in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 1 ALA3397044 organism-based format Scientific Literature 8. ALA3399359 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg Rattus norvegicus 1 ALA3397044 organism-based format Scientific Literature 9. ALA3399362 A Drug metabolism in rat liver microsomes at 5 uM after 15 mins Rattus norvegicus 2 ALA3397044 assay format Scientific Literature 10. ALA3399363 A Ratio of drug level in brain to plasma in Sprague-Dawley rat at 10 mg/kg, ip Rattus norvegicus 1 ALA3397044 organism-based format Scientific Literature 11. ALA3399364 A Ratio of drug level in CSF to plasma in Sprague-Dawley rat at 10 mg/kg, ip Rattus norvegicus 1 ALA3397044 organism-based format Scientific Literature 12. ALA3399365 A Volume of distribution in dog at 0.5 mg/kg, iv Canis lupus familiaris 2 ALA3397044 organism-based format Scientific Literature 13. ALA3399366 A Clearance in dog at 0.5 mg/kg, iv Canis lupus familiaris 2 ALA3397044 organism-based format Scientific Literature 14. ALA3399367 A Half life in dog at 0.5 mg/kg, iv Canis lupus familiaris 2 ALA3397044 organism-based format Scientific Literature 15. ALA3399368 A Tmax in dog at 3 mg/kg, po Canis lupus familiaris 2 ALA3397044 organism-based format Scientific Literature 16. ALA3399369 A Oral bioavailability in dog at 3 mg/kg Canis lupus familiaris 2 ALA3397044 organism-based format Scientific Literature 17. ALA3399370 A Drug excretion in rat urine Rattus norvegicus 1 ALA3397044 tissue-based format Scientific Literature 18. ALA3399371 A Drug metabolism in dog liver microsomes at 5 uM after 15 mins Canis lupus familiaris 2 ALA3397044 assay format Scientific Literature 19. ALA3399372 A Drug excretion in rat bile Rattus norvegicus 1 ALA3397044 tissue-based format Scientific Literature 20. ALA3399373 P Solubility in pH 6.8 phosphate buffer 1 ALA3397044 small-molecule physicochemical format Scientific Literature