| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3399217 | F | Antagonist activity against human OX1 receptor expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated for 30 mins by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA3399218 | F | Antagonist activity against human OX2 receptor expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated for 30 mins by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 3. | ALA3399219 | A | Drug metabolism in human liver microsomes at 5 uM after 15 mins | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 4. | ALA3399220 | A | Volume of distribution in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA3399221 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA3399222 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA3399358 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA3399359 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3399362 | A | Drug metabolism in rat liver microsomes at 5 uM after 15 mins | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 10. | ALA3399363 | A | Ratio of drug level in brain to plasma in Sprague-Dawley rat at 10 mg/kg, ip | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3399364 | A | Ratio of drug level in CSF to plasma in Sprague-Dawley rat at 10 mg/kg, ip | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3399365 | A | Volume of distribution in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA3399366 | A | Clearance in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA3399367 | A | Half life in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA3399368 | A | Tmax in dog at 3 mg/kg, po | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA3399369 | A | Oral bioavailability in dog at 3 mg/kg | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA3399370 | A | Drug excretion in rat urine | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 18. | ALA3399371 | A | Drug metabolism in dog liver microsomes at 5 uM after 15 mins | Canis lupus familiaris | 2 | assay format | Scientific Literature | ||
| 19. | ALA3399372 | A | Drug excretion in rat bile | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 20. | ALA3399373 | P | Solubility in pH 6.8 phosphate buffer | 1 | small-molecule physicochemical format | Scientific Literature |
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