| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3404988 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells after 16 hrs by luciferase reporter assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA3404989 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as CTGF expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 4 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3404992 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as CTGF protein expression preincubated at 407 nM for 1 hr before TGF-beta stimulation measured after 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3406438 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in type 1 collagen alpha1 expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3406439 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in alpha-smooth muscle actin expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3406440 | B | Binding affinity to (AGCCAGACA)9-MLP element (unknown origin) transiently transfected in human HepG2 cells assessed as inhibition of TGF-beta-induced Smad-dependent transcriptional activity preincubated for 1 hr before TGF-beta stimulation measured after 16 hrs by luciferase reporter assay | Not specified | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA3406442 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in mmp2 expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3406443 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in tgf-beta expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3406444 | B | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in plasminogen activator inhibitor-1 expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3406622 | F | Antimigratory activity against human MDA-MB-231 cells assessed as reduction in formation of tubule-like structures at 136 nM after 16 hrs by matrigel assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3406627 | F | Antimigratory activity against human MDA-MB-231 cells assessed as reduction in formation of tubule-like structures after 16 hrs by matrigel assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA5258729 | B | Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase activity incubated for 24 hrs by Promega reporter rene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA5258730 | B | Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activity incubated for 24 hrs by Promega reporter rene assay | Homo sapiens | 4 | cell-based format | Scientific Literature |
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