# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3405600 | F | Antagonist activity at human S1P2 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration incubated 3 mins prior to S1P challenge by fluorescence assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
2. | ALA3405601 | F | Antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration after 3 mins by fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA3405602 | F | Antagonist activity at human S1P3 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration after 3 mins by fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
4. | ALA3405603 | F | Antagonist activity at human LPA2 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration after 3 mins by fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA3405604 | B | Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
6. | ALA3407044 | B | Displacement of [33P]-S1P from human S1P1 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA3407045 | B | Displacement of [33P]-S1P from human S1P3 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA3407046 | B | Displacement of [33P]-S1P from human S1P4 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA3407047 | B | Displacement of [33P]-S1P from human S1P5 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA3407048 | P | Solubility of the compound in phosphate buffer at pH 6.8 after 5 hrs by LC-MS/MS analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA3407049 | A | Permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA3407050 | A | Permeability across basolateral to apical side in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA3407051 | A | Plasma protein binding in human | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
14. | ALA3407052 | A | Plasma protein binding in rat | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
15. | ALA5099154 | B | Binding affinity to S1PR2 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysis | Homo sapiens | 41 | single protein format | Scientific Literature | ||
16. | ALA5099155 | B | Binding affinity to S1PR1 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
17. | ALA5099156 | B | Binding affinity to S1PR3 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
18. | ALA5099157 | B | Binding affinity to S1PR4 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
19. | ALA5099158 | B | Binding affinity to S1PR5 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
20. | ALA5099171 | F | Antiproliferative activity against human HCT-116 cells overexpressing DPD assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature |