# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3404758 | F | Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
2. | ALA3404759 | F | Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
3. | ALA3404760 | A | Apparent permeability across apical to basolateral or basolateral to apical side in human Caco2 cells at 1 uM after 2 hrs by LC/MS/MS analysis | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
4. | ALA3404763 | A | Cmax in rat at 30 mg/kg, po | Rattus norvegicus | 5 | ALA3400104 | organism-based format | Scientific Literature | |
5. | ALA3404765 | A | Half life in rat at 30 mg/kg, po | Rattus norvegicus | 5 | ALA3400104 | organism-based format | Scientific Literature | |
6. | ALA3404767 | A | AUC in rat at 30 mg/kg, po | Rattus norvegicus | 5 | ALA3400104 | organism-based format | Scientific Literature | |
7. | ALA3404926 | A | Oral bioavailability in rat at 30 mg/kg | Rattus norvegicus | 5 | ALA3400104 | organism-based format | Scientific Literature | |
8. | ALA3404928 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | ALA3400104 | organism-based format | Scientific Literature | |
9. | ALA3404929 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | ALA3400104 | organism-based format | Scientific Literature | |
10. | ALA3404930 | A | AUCinf in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | ALA3400104 | organism-based format | Scientific Literature | |
11. | ALA3404931 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | ALA3400104 | organism-based format | Scientific Literature |