# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3404758 | F | Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
2. | ALA3404759 | F | Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
3. | ALA3404760 | A | Apparent permeability across apical to basolateral or basolateral to apical side in human Caco2 cells at 1 uM after 2 hrs by LC/MS/MS analysis | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
4. | ALA3404761 | P | Apparent permeability of the compound at pH 6.2 by PAMPA | 5 | ALA3400104 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3404762 | P | Apparent permeability of the compound at pH 7.4 by PAMPA | 5 | ALA3400104 | small-molecule physicochemical format | Scientific Literature |