#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3404758	F	Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay	Homo sapiens	15	ALA3400104	cell-based format	Scientific Literature
2.	ALA3404759	F	Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay	Homo sapiens	15	ALA3400104	cell-based format	Scientific Literature
3.	ALA3404760	A	Apparent permeability across apical to basolateral or basolateral to apical side in human Caco2 cells at 1 uM after 2 hrs by LC/MS/MS analysis	Homo sapiens	15	ALA3400104	cell-based format	Scientific Literature
4.	ALA3404761	P	Apparent permeability of the compound at pH 6.2 by PAMPA		5	ALA3400104	small-molecule physicochemical format	Scientific Literature
5.	ALA3404762	P	Apparent permeability of the compound at pH 7.4 by PAMPA		5	ALA3400104	small-molecule physicochemical format	Scientific Literature
6.	ALA3404764	A	Cmax in rat at 10 mg/kg, po	Rattus norvegicus	2	ALA3400104	organism-based format	Scientific Literature
7.	ALA3404766	A	Half life in rat at 10 mg/kg, po	Rattus norvegicus	2	ALA3400104	organism-based format	Scientific Literature
8.	ALA3404925	A	AUC in rat at 10 mg/kg, po	Rattus norvegicus	2	ALA3400104	organism-based format	Scientific Literature
9.	ALA3404927	A	Oral bioavailability in rat at 10 mg/kg	Rattus norvegicus	2	ALA3400104	organism-based format	Scientific Literature
10.	ALA3404928	A	Clearance in rat at 1 mg/kg, iv	Rattus norvegicus	7	ALA3400104	organism-based format	Scientific Literature
11.	ALA3404929	A	Half life in rat at 1 mg/kg, iv	Rattus norvegicus	7	ALA3400104	organism-based format	Scientific Literature
12.	ALA3404930	A	AUCinf in rat at 1 mg/kg, iv	Rattus norvegicus	7	ALA3400104	organism-based format	Scientific Literature
13.	ALA3404931	A	Volume of distribution at steady state in rat at 1 mg/kg, iv	Rattus norvegicus	7	ALA3400104	organism-based format	Scientific Literature
14.	ALA3404932	F	In vivo inhibition of CysLT1 receptor in po dosed guinea pig assessed as reduction in LTD4-induced bronchoconstriction	Cavia porcellus	1	ALA3400104	organism-based format	Scientific Literature
15.	ALA3404933	F	In vivo inhibition of CysLT1 receptor in guinea pig assessed as reduction in LTD4-induced bronchoconstriction at 3 mg/kg, po relative to vehicle treated control	Cavia porcellus	1	ALA3400104	organism-based format	Scientific Literature
16.	ALA3404934	F	In vivo inhibition of CysLT1 receptor in guinea pig assessed as reduction in LTD4-induced bronchoconstriction at 10 mg/kg, po relative to vehicle treated control	Cavia porcellus	1	ALA3400104	organism-based format	Scientific Literature
17.	ALA3599260	F	Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins prior to LTD4 addition measured after 1 hr by Fura 2-AM dye-based fluorescence assay	Homo sapiens	36	ALA3596134	cell-based format	Scientific Literature
18.	ALA3599261	F	Antagonist activity at human CysLT2 expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins prior to LTD4 addition measured after 1 hr by Fura 2-AM dye-based fluorescence assay	Homo sapiens	36	ALA3596134	cell-based format	Scientific Literature
19.	ALA3599262	F	Antiasthmatic activity in guinea pig assessed as inhibition of LTD4-induced bronchoconstriction at 1 mg/kg, po administered 1 hr prior to LTD4 challenge measured over 10 mins relative to control	Cavia porcellus	10	ALA3596134	organism-based format	Scientific Literature
20.	ALA3599263	P	Permeability of the compound at 50 uM at pH 6.2 after 4 hrs by PAMPA		14	ALA3596134	small-molecule physicochemical format	Scientific Literature