| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3405734 | B | Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate release detection based malachite green reagent assay | Mycolicibacterium smegmatis | 52 | cell-based format | Scientific Literature | ||
| 2. | ALA3405735 | B | Inhibition of Staphylococcus aureus GyrB at 100 uM | Staphylococcus aureus | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3405736 | B | Inhibition of Escherichia coli GyrB at 100 uM | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3405737 | B | Inhibition of Mycobacterium tuberculosis GyrA/GyrB using relaxed pBR322 substrate incubated for 30 mins by ethidium bromide staining and electrophoresis based DNA supercoiling assay | Mycobacterium tuberculosis | 52 | assay format | Scientific Literature | ||
| 5. | ALA3405738 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 incubated for 7 days by microplate alamar blue assay method | Mycobacterium tuberculosis | 52 | organism-based format | Scientific Literature | ||
| 6. | ALA3405739 | A | Cytotoxicity against mouse RAW264.7 cells assessed as inhibition of cell growth at 50 uM after 48 hrs by MTT assay | Mus musculus | 52 | cell-based format | Scientific Literature | ||
| 7. | ALA3405740 | F | Antimycobacterial activity against extensively drug resistant Mycobacterium tuberculosis | Mycobacterium tuberculosis | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA3405741 | B | Binding affinity to Mycobacterium smegmatis GyrB assessed as increase in protein-compound complex stability by measuring right side positive shift of melting temperature by SYPRO-orange dye based differential scanning fluorimetry | Mycolicibacterium smegmatis | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3405742 | A | Cardiotoxic inhibition of ERG channel in Zebrafish assessed as change in heart rate of atria at 1 uM to 30 uM after 4 hrs | Danio rerio | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3405744 | A | Cardiotoxic inhibition of ERG channel in Zebrafish assessed as change in atrio ventricular beats ratio at 1 uM to 30 uM after 4 hrs | Danio rerio | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3405745 | A | Cardiotoxic inhibition of ERG channel in Zebrafish assessed as change in heart rate of ventricles at 1 uM to 30 uM after 4 hrs | Danio rerio | 1 | organism-based format | Scientific Literature |
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