| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3405046 | B | Inhibition of Orai-mediated calcium entry in human Jurkat E6-1 cells after 1 hr by FLIPR assay | Homo sapiens | 23 | ALA3399948 | cell-based format | Scientific Literature | |
| 2. | ALA3405047 | B | Inhibition of Orai channel in phytohemagglutinin-stimulated human Jurkat E6-1 cells assessed as NFAT-induced transcription measured as IL-2 level after 20 hrs by ELISA | Homo sapiens | 23 | ALA3399948 | cell-based format | Scientific Literature | |
| 3. | ALA3405048 | B | Inhibition of human Orai1/STIM1 expressed in HEK293 cells assessed as inhibition of channel-mediated calcium current by electrophysiology assay in presence of 10 mM EGTA | Homo sapiens | 3 | ALA3399948 | cell-based format | Scientific Literature | |
| 4. | ALA3405049 | F | Inhibition of degranulation in human LAD2 cells assessed as inhibition of IgE-induced beta-hexosaminidase release preincubated for 30 mins by p-nitrophenyl-N-acetyl-D-glucosamide-based spectrophotometric assay | Homo sapiens | 3 | ALA3399948 | cell-based format | Scientific Literature | |
| 5. | ALA3405050 | F | Inhibition of IL2 secretion in rat whole blood after 24 hrs by Rat IL-2 DuoSet assay | Rattus norvegicus | 3 | ALA3399948 | tissue-based format | Scientific Literature | |
| 6. | ALA3405051 | A | Cytotoxicity against CHO cells | Cricetulus griseus | 3 | ALA3399948 | cell-based format | Scientific Literature | |
| 7. | ALA3405052 | A | Drug metabolism in rat liver microsomes at 5 uM after 30 mins in presence of NADPH | Rattus norvegicus | 3 | ALA3399948 | assay format | Scientific Literature | |
| 8. | ALA3405053 | A | Drug metabolism in human liver microsomes at 5 uM after 30 mins in presence of NADPH | Homo sapiens | 3 | ALA3399948 | assay format | Scientific Literature | |
| 9. | ALA3405054 | A | Passive permeability of the compound at 20 uM by PAMPA | 3 | ALA3399948 | assay format | Scientific Literature | ||
| 10. | ALA3405062 | P | Solubility of the compound in water | 5 | ALA3399948 | small-molecule physicochemical format | Scientific Literature | ||
| 11. | ALA3405063 | A | Plasma protein binding in Wistar rat | Rattus norvegicus | 1 | ALA3399948 | cell-free format | Scientific Literature |
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