# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3405070 | Functional | Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by HTRF method relative to control | Homo sapiens | 35 | ALA3399915 | cell-based format | Scientific Literature | |
2. | ALA3405214 | ADME | Protein binding in rat brain by equilibrium dialysis method | Rattus norvegicus | 4 | ALA3399915 | tissue-based format | Scientific Literature | |
3. | ALA3405221 | ADME | Plasma concentration in rat at 10 mg/kg, ip after 30 mins | Rattus norvegicus | 4 | ALA3399915 | organism-based format | Scientific Literature | |
4. | ALA3405222 | ADME | Drug uptake in rat CSF at 10 mg/kg, ip after 30 mins | Rattus norvegicus | 4 | ALA3399915 | organism-based format | Scientific Literature | |
5. | ALA3405223 | ADME | Drug uptake in rat brain at 10 mg/kg, ip after 30 mins | Rattus norvegicus | 4 | ALA3399915 | organism-based format | Scientific Literature | |
6. | ALA3405224 | ADME | Drug uptake in rat lung at 10 mg/kg, ip after 30 mins | Rattus norvegicus | 4 | ALA3399915 | organism-based format | Scientific Literature | |
7. | ALA3405225 | ADME | Plasma concentration in rat at 30 mg/kg, ip after 30 mins | Rattus norvegicus | 1 | ALA3399915 | organism-based format | Scientific Literature | |
8. | ALA3405226 | ADME | Drug uptake in rat CSF at 30 mg/kg, ip after 30 mins | Rattus norvegicus | 1 | ALA3399915 | organism-based format | Scientific Literature | |
9. | ALA3405227 | ADME | Drug uptake in rat brain at 30 mg/kg, ip after 30 mins | Rattus norvegicus | 1 | ALA3399915 | organism-based format | Scientific Literature | |
10. | ALA3405228 | ADME | Drug uptake in rat lung at 30 mg/kg, ip after 30 mins | Rattus norvegicus | 1 | ALA3399915 | organism-based format | Scientific Literature | |
11. | ALA3405229 | ADME | Clearance in mouse at 10 mg/kg, ip | Mus musculus | 4 | ALA3399915 | organism-based format | Scientific Literature | |
12. | ALA3721239 | Functional | Modulator activity at GPR88 (unknown origin) expressed in cell membranes incubated for 1 hr by liquid scintillation counting based [35S]GTPgammaS binding assay | Homo sapiens | 18 | ALA3714734 | cell-based format | Patent Bioactivity Data | |
13. | ALA3721240 | Functional | Modulator activity at GPR88 (unknown origin) incubated for 30 mins by cell based cAMP HTRF assay | Homo sapiens | 18 | ALA3714734 | cell-based format | Patent Bioactivity Data |