| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3413142 | B | Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis | Homo sapiens | 64 | single protein format | Scientific Literature | ||
| 2. | ALA3413143 | B | Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis | Homo sapiens | 64 | cell-based format | Scientific Literature | ||
| 3. | ALA3413144 | P | Lipophilicity, log P of the compound at pH 7 | 33 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA3413145 | P | Aqueous solubility of the compound | 13 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA3413146 | A | Permeability from basolateral to apical side in human Caco2 cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA3413147 | A | Permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA3413301 | A | Effective efflux ratio of apparent permeability in MDCK cells overexpressing PGP at 10 uM to wild-type MDCK cells at 10 uM | Canis lupus familiaris | 10 | cell-based format | Scientific Literature | ||
| 8. | ALA3413302 | A | Effective efflux ratio of apparent permeability in MDCK cells overexpressing BCRP at 10 uM to wild-type MDCK cells at 10 uM | Canis lupus familiaris | 10 | cell-based format | Scientific Literature | ||
| 9. | ALA3413303 | A | Intrinsic clearance in human liver microsomes assessed per mg of protein | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 10. | ALA3413304 | A | Intrinsic clearance in rat liver microsomes assessed per mg of protein | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
| 11. | ALA3413305 | A | Intrinsic clearance in mouse liver microsomes assessed per mg of protein | Mus musculus | 10 | assay format | Scientific Literature | ||
| 12. | ALA3413306 | B | Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis | Mus musculus | 5 | single protein format | Scientific Literature | ||
| 13. | ALA3413307 | B | Inhibition of rat KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis | Rattus norvegicus | 5 | single protein format | Scientific Literature | ||
| 14. | ALA3413308 | B | Inhibition of KMO in human PBMC | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 15. | ALA3413309 | B | Inhibition of KMO in rat microglia cells | Rattus norvegicus | 5 | cell-based format | Scientific Literature |
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