# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3413038 | B | Inhibition of hedgehog signaling in mouse C3H10T1/2 cells assessed as reduction in Gli1 mRNA level at 5 uM after 24 hrs by quantitative PCR analysis relative to control | Mus musculus | 34 | cell-based format | Scientific Literature | ||
2. | ALA3413039 | A | Activation of VDR in mouse C3H10T1/2 cells assessed as up-regulation of Cyp24A1 mRNA at 5 uM after 24 hrs by quantitative PCR analysis relative to control | Mus musculus | 34 | cell-based format | Scientific Literature | ||
3. | ALA3413040 | B | Inhibition of hedgehog signaling in mouse C3H10T1/2 cells assessed as reduction in Gli1 mRNA level after 24 hrs by quantitative PCR analysis | Mus musculus | 15 | cell-based format | Scientific Literature | ||
4. | ALA3413041 | B | Inhibition of hedgehog signaling in mouse ASZ cells assessed as reduction in Gli1 mRNA level after 24 hrs by quantitative PCR analysis | Mus musculus | 15 | cell-based format | Scientific Literature | ||
5. | ALA3413043 | A | Activation of VDR in mouse ASZ cells assessed as up-regulation of Cyp24A1 mRNA at 5 uM after 24 hrs by quantitative PCR analysis relative to control | Mus musculus | 14 | cell-based format | Scientific Literature | ||
6. | ALA3413044 | B | Binding affinity to full length human VDR by fluorescent displacement assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
7. | ALA4384335 | F | Antiproliferative activity against medulloblastoma cells derived from conditional patched knockout mouse after 48 hrs by [3H]-thymidine incorporation assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
8. | ALA4384336 | A | Half life in human liver microsomes at 1 uM by LC-MS/MS analysis | Homo sapiens | 10 | microsome format | Scientific Literature | ||
9. | ALA4384337 | A | Clearance in human liver microsomes assessed per mg protein at 1 uM by LC-MS/MS analysis | Homo sapiens | 11 | microsome format | Scientific Literature | ||
10. | ALA4384338 | P | Kinetic solubility of the compound in pH 4 phosphate buffered saline | 11 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA4384339 | P | Kinetic solubility of the compound in pH 7.4 phosphate buffered saline | 11 | small-molecule physicochemical format | Scientific Literature |