# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3412610 | F | Antiviral activity against HIV-1 SF33 infected in TZM-bl cells after 2 days by luciferase reporter gene assay | Human immunodeficiency virus 1 | 8 | ALA3407456 | organism-based format | Scientific Literature | |
2. | ALA3412775 | A | Cytotoxicity against human TZM-bl cells assessed as reduction cell viability at <12.5 uM after 2 days by XTT assay | Homo sapiens | 8 | ALA3407456 | cell-based format | Scientific Literature | |
3. | ALA3412776 | B | Binding affinity to HIV1 gp41 (46 residues) by surface plasmon resonance method | Human immunodeficiency virus 1 | 3 | ALA3407456 | single protein format | Scientific Literature | |
4. | ALA3412777 | B | Binding affinity to HIV1 gp41 (46 residues) assessed as effect on protein secondary structure measured as alpha-helicity in PBS buffer at pH 7.2 by circular dichroism assay (Rvb = 117 %) | Human immunodeficiency virus 1 | 3 | ALA3407456 | single protein format | Scientific Literature | |
5. | ALA3412779 | A | Plasma concentration in Sprague-Dawley rat at 1.7 umol/kg, sc after 24 hrs | Rattus norvegicus | 1 | ALA3407456 | organism-based format | Scientific Literature | |
6. | ALA3412780 | A | Half life in Sprague-Dawley rat at 1.7 umol/kg, sc after 6 hrs | Rattus norvegicus | 3 | ALA3407456 | organism-based format | Scientific Literature |