# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3782901 | Binding | Displacement of [3H]SP from human NK1 receptor transfected in CHO cells by liquid scintillation counting method | Homo sapiens | 10 | ALA3779864 | cell-based format | Scientific Literature | |
2. | ALA3783006 | Binding | Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction | Cavia porcellus | 11 | ALA3779864 | tissue-based format | Scientific Literature | |
3. | ALA3783007 | Binding | Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | Mus musculus | 11 | ALA3779864 | tissue-based format | Scientific Literature | |
4. | ALA3783008 | Binding | Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 2 hrs | Rattus norvegicus | 11 | ALA3779864 | cell membrane format | Scientific Literature | |
5. | ALA3783009 | Binding | Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane after 2 hrs | Rattus norvegicus | 11 | ALA3779864 | cell membrane format | Scientific Literature | |
6. | ALA3783010 | Binding | Antagonist activity against human NK1 receptor expressed in CHO-K1 cells by aequorin luminescence assay based Schild's plot analysis | Homo sapiens | 10 | ALA3779864 | cell-based format | Scientific Literature | |
7. | ALA3411100 | Binding | Antagonist activity at human NK1 receptor expressed in CHO cells by luminescence assay in presence of SP peptide | Homo sapiens | 16 | ALA3407477 | cell-based format | Scientific Literature | |
8. | ALA3411101 | Binding | Displacement of [3H]SP from human NK1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting analysis | Homo sapiens | 16 | ALA3407477 | cell-based format | Scientific Literature | |
9. | ALA3411102 | Binding | Activation of MOR in guinea pig ileum | Cavia porcellus | 14 | ALA3407477 | tissue-based format | Scientific Literature | |
10. | ALA3411105 | Binding | Activation of DOR in mouse vas deferens | Mus musculus | 16 | ALA3407477 | single protein format | Scientific Literature | |
11. | ALA3411022 | Binding | Displacement of [3H]DAMGO from rat brain MOR after 2 hrs | Rattus norvegicus | 16 | ALA3407477 | assay format | Scientific Literature | |
12. | ALA3411023 | Binding | Displacement of [3H]DSLET from rat brain DOR after 2 hrs | Rattus norvegicus | 16 | ALA3407477 | assay format | Scientific Literature | |
13. | ALA3411024 | Binding | Selectivity ratio of Ki for rat brain DOR to Ki for rat brain MOR | Rattus norvegicus | 16 | ALA3407477 | assay format | Scientific Literature | |
14. | ALA3411026 | Functional | Antinociceptive activity in Wistar rat at 0.1 to 11 nmol, it after 30 mins to 2 hrs by tail flick test | Rattus norvegicus | 1 | ALA3407477 | organism-based format | Scientific Literature | |
15. | ALA3411030 | Toxicity | Toxicity in Wistar rat assessed as seizures at 9.5 nmol, iv | Rattus norvegicus | 2 | ALA3407477 | organism-based format | Scientific Literature | |
16. | ALA3411031 | Toxicity | Toxicity in Wistar rat assessed as death at 9.5 nmol, iv | Rattus norvegicus | 2 | ALA3407477 | organism-based format | Scientific Literature | |
17. | ALA3411033 | Functional | Antinociceptive activity in C57Bl6 mouse at 12.5 umol/kg, iv after 30 mins by tail flick test relative to morphine | Mus musculus | 1 | ALA3407477 | organism-based format | Scientific Literature | |
18. | ALA3411037 | Functional | Antiallodynic effect in Wistar rat chronic constriction injury model at 0.1 to 1 nmol, it measured 7 days post CCI challenge by Von Frey test | Rattus norvegicus | 3 | ALA3407477 | organism-based format | Scientific Literature | |
19. | ALA3411069 | Functional | Antiallodynic effect in Wistar rat chronic constriction injury model at 1 nmol, it measured 7 days post CCI challenge by Von Frey test | Rattus norvegicus | 2 | ALA3407477 | organism-based format | Scientific Literature | |
20. | ALA3411070 | Functional | Antinociceptive activity in Wistar rat at 1 nmol, it after 30 mins by tail flick test | Rattus norvegicus | 2 | ALA3407477 | organism-based format | Scientific Literature |