| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3413740 | F | Negative ionotropic activity in guinea pig left atrium assessed as decrease in developed tension driven at 1 Hz | Cavia porcellus | 11 | ALA3407488 | tissue-based format | Scientific Literature | |
| 2. | ALA3413882 | F | Negative chronotropic activity in guinea pig left atrium assessed as decrease in atrial rate on spontaneous beating at 10'-5 M relative to control | Cavia porcellus | 3 | ALA3407488 | tissue-based format | Scientific Literature | |
| 3. | ALA3413886 | B | Antagonist activity at Cav1.2a in K+-depolarized guinea pig aortic strips assessed as inhibition of calcium-induced contraction at 10'-4 M relative to control | Cavia porcellus | 10 | ALA3407488 | tissue-based format | Scientific Literature | |
| 4. | ALA3413890 | A | Antagonist activity at Cav1.2b in K+-depolarized guinea pig ileum longitudinal smooth muscle assessed as inhibition of calcium-induced contraction at 10'-4 M relative to control | Cavia porcellus | 8 | ALA3407488 | tissue-based format | Scientific Literature | |
| 5. | ALA3413894 | F | Negative ionotropic activity in guinea pig left atrium assessed as decrease in developed tension driven at 1 Hz at 5 x 10'-6 M relative to control | Cavia porcellus | 3 | ALA3407488 | tissue-based format | Scientific Literature | |
| 6. | ALA3413897 | A | Antagonist activity at Cav1.2b in K+-depolarized guinea pig ileum longitudinal smooth muscle assessed as inhibition of calcium-induced contraction | Cavia porcellus | 9 | ALA3407488 | tissue-based format | Scientific Literature | |
| 7. | ALA3413899 | F | Ratio of diltiazem EC50 to compound EC50 for negative ionotropic activity in guinea pig left atrium assessed as decrease in developed tension driven at 1 Hz | Cavia porcellus | 2 | ALA3407488 | tissue-based format | Scientific Literature | |
| 8. | ALA3820761 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 4 mins by LC-MS analysis | Homo sapiens | 11 | ALA3817843 | tissue-based format | Scientific Literature | |
| 9. | ALA3820762 | A | Half life in human liver microsomes assessed as CYP-mediated compound degradation at 1 uM by LC-MS analysis | Homo sapiens | 10 | ALA3817843 | tissue-based format | Scientific Literature | |
| 10. | ALA3821541 | A | Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 40 mins by LC-MS analysis | Homo sapiens | 11 | ALA3817843 | tissue-based format | Scientific Literature | |
| 11. | ALA3821691 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS analysis | Homo sapiens | 11 | ALA3817843 | tissue-based format | Scientific Literature | |
| 12. | ALA3821692 | A | Intrinsic clearance in human liver microsomes at 1 uM after 2 to 60 mins by LC-MS analysis in presence of NADPH | Homo sapiens | 10 | ALA3817843 | tissue-based format | Scientific Literature | |
| 13. | ALA3821693 | A | Stability in human liver microsomes at 1 uM after 2 to 60 mins by LC-MS analysis in absence of NADPH | Homo sapiens | 10 | ALA3817843 | tissue-based format | Scientific Literature | |
| 14. | ALA3821694 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 30 mins by LC-MS analysis | Homo sapiens | 11 | ALA3817843 | tissue-based format | Scientific Literature | |
| 15. | ALA3821695 | A | Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate after 20 mins by LC-MS analysis | Homo sapiens | 11 | ALA3817843 | tissue-based format | Scientific Literature | |
| 16. | ALA3821882 | A | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate after 5 mins by LC-MS analysis | Homo sapiens | 11 | ALA3817843 | tissue-based format | Scientific Literature |
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