| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3412689 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA3412690 | A | Cytotoxicity against RFC-deficient Chinese hamster R2 cells assessed as growth inhibition after 96 hrs by CellTiter-Blue assay | Cricetulus griseus | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA3412691 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA3412692 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA3412693 | A | Cytotoxicity against PCFT-deficient Chinese hamster R2(VC) cells assessed as growth inhibition after 96 hrs by CellTiter-Blue assay | Cricetulus griseus | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA3412694 | F | Antiproliferative activity against human KB cells expressing RFC/FRalpha/PCFT after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA3412695 | F | Antiproliferative activity against human KB cells expressing RFC/FRalpha/PCFT after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3412697 | B | Inhibition of GARFTase/AICARFTase in human KB cells expressing RFC/FRalpha/PCFT assessed as cell growth inhibition at 1 to 1000 nM after 96 hrs by CellTiter-Blue assay in presence of 60 uM adenosine | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3412860 | B | Inhibition of GARFTase/AICARFTase in human KB cells expressing RFC/FRalpha/PCFT assessed as cell growth inhibition at 1 to 1000 nM after 96 hrs by CellTiter-Blue assay in presence of 10 uM thymidine | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3412861 | B | Inhibition of AICARFTase in human KB cells expressing RFC/FRalpha/PCFT assessed as cell growth inhibition at 1 to 1000 nM after 96 hrs by CellTiter-Blue assay in presence of 320 uM AICA | Homo sapiens | 4 | cell-based format | Scientific Literature |
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