# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3411298 | B | Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATP | Homo sapiens | 45 | ALA3407489 | single protein format | Scientific Literature | |
2. | ALA3411299 | B | Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATP | Homo sapiens | 42 | ALA3407489 | single protein format | Scientific Literature | |
3. | ALA3411301 | B | Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATP | Homo sapiens | 15 | ALA3407489 | single protein format | Scientific Literature | |
4. | ALA3411302 | B | Inhibition of human JNK3 using ATF2 substrate, ATP and [gamma33P]ATP | Homo sapiens | 15 | ALA3407489 | single protein format | Scientific Literature | |
5. | ALA3411303 | A | Inhibition of CYP1A2 (unknown origin) assessed as reduction in phenaceten demethylation to acetaminophen at 10 uM | Homo sapiens | 15 | ALA3407489 | single protein format | Scientific Literature | |
6. | ALA3411304 | A | Inhibition of CYP2C9 (unknown origin) assessed as reduction in tolbutamide hydroxylation to hydrocytolbutamide at 10 uM | Homo sapiens | 15 | ALA3407489 | single protein format | Scientific Literature | |
7. | ALA3411305 | A | Inhibition of CYP2D6 (unknown origin) assessed as reduction in bufuralol hydroxylation to 4'-Hydroxybufuralol at 10 uM | Homo sapiens | 15 | ALA3407489 | single protein format | Scientific Literature | |
8. | ALA3411306 | A | Inhibition of CYP3A4 (unknown origin) assessed as reduction in midazolam hydroxylation to 1'-Hydroxymidazolam at 10 uM | Homo sapiens | 15 | ALA3407489 | single protein format | Scientific Literature | |
9. | ALA3411313 | A | Half life in human liver microsomes | Homo sapiens | 15 | ALA3407489 | assay format | Scientific Literature | |
10. | ALA3411314 | A | Half life in rat liver microsomes | Rattus norvegicus | 15 | ALA3407489 | assay format | Scientific Literature | |
11. | ALA3411315 | B | Inhibition of Limk1 in rat A7r5 cells assessed as reduction in cofilin phosphorylation by Western blot method | Rattus norvegicus | 15 | ALA3407489 | cell-based format | Scientific Literature | |
12. | ALA3411319 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS and HPLC method | Rattus norvegicus | 14 | ALA3407489 | organism-based format | Scientific Literature | |
13. | ALA3411320 | A | Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS and HPLC method | Rattus norvegicus | 14 | ALA3407489 | organism-based format | Scientific Literature | |
14. | ALA3411321 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS and HPLC method | Rattus norvegicus | 14 | ALA3407489 | organism-based format | Scientific Literature | |
15. | ALA3411322 | A | AUC in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS and HPLC method | Rattus norvegicus | 14 | ALA3407489 | organism-based format | Scientific Literature | |
16. | ALA3411323 | A | Cmax in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS and HPLC method | Rattus norvegicus | 14 | ALA3407489 | organism-based format | Scientific Literature | |
17. | ALA3411324 | A | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg by LC-MS/MS and HPLC method | Rattus norvegicus | 14 | ALA3407489 | organism-based format | Scientific Literature | |
18. | ALA5244624 | B | Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid method | Homo sapiens | 19 | ALA5244212 | cell-based format | Scientific Literature |