| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3420957 | B | Inhibition of Escherichia coli RNase H pre-incubated for 10 mins before HTS-1 RNA/DNA duplex substrate addition by fluorescence assay | Escherichia coli | 11 | assay format | Scientific Literature | ||
| 2. | ALA3418034 | B | Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed cleavage using HTS-2 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 21 | single protein format | Scientific Literature | ||
| 3. | ALA3418035 | B | Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed cleavage using HTS-3 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 21 | single protein format | Scientific Literature | ||
| 4. | ALA3418036 | B | Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 21 | single protein format | Scientific Literature | ||
| 5. | ALA3418037 | B | Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by liquid scintillation spectrometry | Human immunodeficiency virus 1 | 21 | single protein format | Scientific Literature | ||
| 6. | ALA3418038 | B | Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 7 | single protein format | Scientific Literature | ||
| 7. | ALA3418039 | B | Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end directed cleavage using HTS-1 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 7 | single protein format | Scientific Literature | ||
| 8. | ALA3418040 | B | Inhibition of HIV1 reverse transcriptase Y181C mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by liquid scintillation spectrometry | Human immunodeficiency virus 1 | 7 | single protein format | Scientific Literature | ||
| 9. | ALA3418041 | B | Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 7 | single protein format | Scientific Literature | ||
| 10. | ALA3418042 | B | Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end directed cleavage using HTS-1 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 7 | single protein format | Scientific Literature | ||
| 11. | ALA3418254 | B | Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by liquid scintillation spectrometry | Human immunodeficiency virus 1 | 7 | single protein format | Scientific Literature | ||
| 12. | ALA3418255 | B | Inhibition of Moloney murine leukemia virus reverse transcriptase associated RNase H pre-incubated for 10 mins before HTS-1 RNA/DNA duplex substrate addition by fluorescence assay | Moloney murine leukemia virus | 11 | assay format | Scientific Literature | ||
| 13. | ALA3418256 | B | Inhibition of Moloney murine leukemia virus reverse transcriptase polymerase activity using Td100/Pd18 DNA-DNA substrate incubated for 30 mins by fluorescence assay | Moloney murine leukemia virus | 11 | single protein format | Scientific Literature | ||
| 14. | ALA3418257 | B | Inhibition of HIV integrase pre-incubated for 10 mins before DNA substrate addition | Human immunodeficiency virus | 20 | single protein format | Scientific Literature | ||
| 15. | ALA3418258 | B | Selectivity index, ratio of IC50 for HIV integrase to IC50 for HIV1 recombinant reverse transcriptase associated catalytically active RNase H-mediated domain internal cleavage activity | 20 | assay format | Scientific Literature | |||
| 16. | ALA3418276 | B | Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using HTS-1 RNA/DNA duplex substrate by fluorescence assay | Human immunodeficiency virus 1 | 21 | single protein format | Scientific Literature |
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