| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3420247 | B | Inhibition of HO1 in Sprague-Dawley rat spleen microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam spectrophotometry | Rattus norvegicus | 15 | tissue-based format | Scientific Literature | ||
| 2. | ALA3420440 | B | Inhibition of HO2 in Sprague-Dawley rat brain microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam spectrophotometry | Rattus norvegicus | 22 | assay format | Scientific Literature | ||
| 3. | ALA3420441 | F | Cytotoxicity against human MDA-MB-231 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA3420442 | F | Cytotoxicity against human MCF7 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA3420443 | F | Cytotoxicity against human DU145 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA3420444 | F | Cytotoxicity against human PC3 cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA3420445 | F | Cytotoxicity against human LNCAP cells incubated for 72 hrs by sulforhodamine B assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA3420446 | A | Cytotoxicity against MDCK cells incubated for 72 hrs by sulforhodamine B assay | Canis lupus familiaris | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA3420447 | U | Selectivity index, ratio of IC50 for MDCK cells to IC50 human MDA-MB-231 cells | 5 | cell-based format | Scientific Literature | |||
| 10. | ALA3420448 | U | Selectivity index, ratio of IC50 for MDCK cells to IC50 human MCF7 cells | 5 | cell-based format | Scientific Literature | |||
| 11. | ALA3420449 | U | Selectivity index, ratio of IC50 for MDCK cells to IC50 human DU145 cells | 5 | cell-based format | Scientific Literature | |||
| 12. | ALA3420450 | U | Selectivity index, ratio of IC50 for MDCK cells to IC50 human PC3 cells | 5 | cell-based format | Scientific Literature | |||
| 13. | ALA3420451 | U | Selectivity index, ratio of IC50 for MDCK cells to IC50 human LNCAP cells | 5 | cell-based format | Scientific Literature | |||
| 14. | ALA4148788 | B | Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | Rattus norvegicus | 25 | microsome format | Scientific Literature | ||
| 15. | ALA4148789 | B | Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | Rattus norvegicus | 25 | microsome format | Scientific Literature | ||
| 16. | ALA4148790 | B | Selectivity index, ratio of IC50 for HO-2 in Sprague-Dawley albino rat brain microsomes to IC50 for HO-1 in Sprague-Dawley albino rat spleen microsomes | Rattus norvegicus | 19 | assay format | Scientific Literature |
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