# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3420247 | Binding | Inhibition of HO1 in Sprague-Dawley rat spleen microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam spectrophotometry | Rattus norvegicus | 15 | ALA3414484 | tissue-based format | Scientific Literature | |
2. | ALA3420440 | Binding | Inhibition of HO2 in Sprague-Dawley rat brain microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam spectrophotometry | Rattus norvegicus | 22 | ALA3414484 | assay format | Scientific Literature | |
3. | ALA4148788 | Binding | Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | Rattus norvegicus | 25 | ALA4145549 | microsome format | Scientific Literature | |
4. | ALA4148789 | Binding | Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | Rattus norvegicus | 25 | ALA4145549 | microsome format | Scientific Literature | |
5. | ALA4148790 | Binding | Selectivity index, ratio of IC50 for HO-2 in Sprague-Dawley albino rat brain microsomes to IC50 for HO-1 in Sprague-Dawley albino rat spleen microsomes | Rattus norvegicus | 19 | ALA4145549 | assay format | Scientific Literature |