| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3420247 | B | Inhibition of HO1 in Sprague-Dawley rat spleen microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam spectrophotometry | Rattus norvegicus | 15 | tissue-based format | Scientific Literature | ||
| 2. | ALA3420440 | B | Inhibition of HO2 in Sprague-Dawley rat brain microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam spectrophotometry | Rattus norvegicus | 22 | assay format | Scientific Literature | ||
| 3. | ALA4148788 | B | Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | Rattus norvegicus | 25 | microsome format | Scientific Literature | ||
| 4. | ALA4148789 | B | Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | Rattus norvegicus | 25 | microsome format | Scientific Literature | ||
| 5. | ALA4148790 | B | Selectivity index, ratio of IC50 for HO-2 in Sprague-Dawley albino rat brain microsomes to IC50 for HO-1 in Sprague-Dawley albino rat spleen microsomes | Rattus norvegicus | 19 | assay format | Scientific Literature |
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