# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3420275 | B | Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISA | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
2. | ALA3420276 | B | Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrate | Homo sapiens | 27 | single protein format | Scientific Literature | ||
3. | ALA3420277 | B | Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate | Homo sapiens | 27 | single protein format | Scientific Literature | ||
4. | ALA3420550 | B | Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate | Homo sapiens | 27 | single protein format | Scientific Literature | ||
5. | ALA3420551 | P | Solubility of the compound in PBS measured after overnight incubation by LYSA assay | 27 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3420552 | A | Intrinsic clearance in human liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured over 30 mins by LC-MS/MS analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
7. | ALA3420553 | A | Intrinsic clearance in mouse liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured over 30 mins by LC-MS/MS analysis | Mus musculus | 5 | assay format | Scientific Literature | ||
8. | ALA3420555 | B | Inhibition of HDAC1/HDAC2/HDAC3 in human HeLa cells assessed as induction of p21 gene expression at 3 to 10 uM after 15 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA3420557 | B | Inhibition of HDAC6 in human NCI-H929 cells assessed as induction of tubulin acetylation after 24 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA3420558 | A | Plasma clearance in ICR mouse | Mus musculus | 6 | organism-based format | Scientific Literature | ||
11. | ALA3420559 | A | AUC (0 to infinity) in ICR mouse at 10 mg/kg, iv | Mus musculus | 3 | organism-based format | Scientific Literature | ||
12. | ALA3420561 | A | Half life in ICR mouse at 10 mg/kg, iv | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA3420563 | A | AUC (0 to infinity) in ICR mouse at 100 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA3420564 | A | Oral bioavailability in ICR mouse at 100 mg/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA3420795 | A | Cmax in ICR mouse at 100 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature |