# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3418055 | A | Cytotoxicity against human Huh7.5 cells after 48 hrs by MTS assay | Homo sapiens | 44 | ALA3414521 | cell-based format | Scientific Literature | |
2. | ALA3418056 | F | Antiviral activity against HCV genotype 1b infected in HuH7/Rep-Feo1b cells at 50 uM by firefly luciferase reporter gene assay | Hepacivirus hominis | 44 | ALA3414521 | cell-based format | Scientific Literature | |
3. | ALA3418057 | F | Antiviral activity against HCV genotype 1b infected in HuH7/Rep-Feo1b cells by firefly luciferase reporter gene assay | Hepacivirus hominis | 44 | ALA3414521 | cell-based format | Scientific Literature | |
4. | ALA3418058 | U | Selectivity index, ratio of CC50 for human Huh7.5 cells to EC50 for HCV genotype 1b infected in HuH7/Rep-Feo1b cells | 44 | ALA3414521 | cell-based format | Scientific Literature | ||
5. | ALA3418059 | F | Antiviral activity against HCV genotype 2a infected in HuH7.5-FGR-JC1_Rluc2A cells at 50 uM by firefly luciferase reporter gene assay | Hepacivirus hominis | 44 | ALA3414521 | assay format | Scientific Literature | |
6. | ALA3418060 | F | Antiviral activity against HCV genotype 2a infected in HuH7.5-FGR-JC1_Rluc2A cells by firefly luciferase reporter gene assay | Hepacivirus hominis | 44 | ALA3414521 | assay format | Scientific Literature | |
7. | ALA3418061 | U | Selectivity index, ratio of CC50 for human Huh7.5 cells to EC50 for HCV genotype 2a infected in HuH7.5-FGR-JC1_Rluc2A cells | 44 | ALA3414521 | cell-based format | Scientific Literature | ||
8. | ALA3418062 | F | Antiviral activity against HCV genotype 1b infected in human MH14 cells assessed as inhibition of replication after 48 hrs by RT-PCR analysis | Hepacivirus hominis | 1 | ALA3414521 | cell-based format | Scientific Literature | |
9. | ALA3418063 | B | Inhibition of recombinant HCV hexa histidine-tagged NS5B Cdelta21 RNA dependent RNA polymerase expressed in Escherichia coli at 50 uM after 60 mins by liquid scintillation counting analysis | Hepatitis C virus | 5 | ALA3414521 | assay format | Scientific Literature | |
10. | ALA3418064 | B | Inhibition of HCV Con1 genotype 1b C-terminal His-tagged NS3 helicase lacking N-terminal protease using fluorescent DNA as substrate at 500 uM | Hepatitis C virus (isolate Con1) | 5 | ALA3414521 | assay format | Scientific Literature | |
11. | ALA3418065 | B | Inhibition of HCV Con1 genotype 1b C-terminal His-tagged NS3 helicase lacking N-terminal protease using ATP/RNA as substrate after 15 mins by malachite green-based assy | Hepatitis C virus (isolate Con1) | 5 | ALA3414521 | assay format | Scientific Literature | |
12. | ALA3418066 | B | Effect on HCV IRES-mediated translation infected in human Huh 7.5 cells by dual-glo luciferase assay | Hepacivirus hominis | 1 | ALA3414521 | cell-based format | Scientific Literature | |
13. | ALA3418067 | A | Effect on cyclooxygenase-2 (unknown origin)-mediated HCV replication in human MH14 cells transfected with pCOX-2-Fluc by luciferase reporter gene assay | Homo sapiens | 1 | ALA3414521 | cell-based format | Scientific Literature | |
14. | ALA3418068 | A | Effect on heme oxygenase-1 (unknown origin)-mediated HCV replication in human MH14 cells transfected with pHO-1-Luc by luciferase reporter gene assay | Homo sapiens | 1 | ALA3414521 | cell-based format | Scientific Literature | |
15. | ALA3418069 | A | Effect on interferon-stimulated response element (unknown origin)-mediated HCV replication in human MH14 cells transfected with pISRE-Luc by luciferase reporter gene assay | Homo sapiens | 1 | ALA3414521 | cell-based format | Scientific Literature | |
16. | ALA3418070 | A | Effect on anti-oxidant response element (unknown origin)-mediated HCV replication in human MH14 cells transfected with p3xARE-Luc by luciferase reporter gene assay | Homo sapiens | 1 | ALA3414521 | cell-based format | Scientific Literature |