# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3420060 | B | Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 8 | ALA3414500 | cell membrane format | Scientific Literature | |
2. | ALA3420062 | B | Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 S31N mutant channel expressed in Xenopus oocyte plasma membranes at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 8 | ALA3414500 | cell membrane format | Scientific Literature | |
3. | ALA3420248 | B | Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 8 | ALA3414500 | cell membrane format | Scientific Literature | |
4. | ALA4270383 | B | Inhibition of Influenza A virus AM2 S31N mutant expressed in xenopus laevis frog oocytes assessed as inhibition of channel current at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus | 20 | ALA4266060 | cell-based format | Scientific Literature | |
5. | ALA4270384 | B | Inhibition of Influenza A virus AM2 expressed in xenopus laevis frog oocytes assessed as inhibition of channel current at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus | 20 | ALA4266060 | cell-based format | Scientific Literature | |
6. | ALA4270385 | F | Antiviral activity against Influenza A virus (A/California/07/2009(H1N1)) infected in MDCK cells expressing ST6Gal-1 assessed as plaque formation at 10 uM pretreated with virus for 30 mins followed by viral infection measured after 2 to 3 days by naphthalene black dye based assay relative to control | Influenza A virus | 20 | ALA4266060 | organism-based format | Scientific Literature | |
7. | ALA4270386 | F | Antiviral activity against Influenza A virus (A/California/07/2009(H1N1)) infected in MDCK cells expressing ST6Gal-1 assessed as reduction in plaque formation pretreated with virus for 30 mins followed by viral infection measured after 2 to 3 days by naphthalene black dye based assay | Influenza A virus | 21 | ALA4266060 | organism-based format | Scientific Literature | |
8. | ALA4270387 | A | Cytotoxicity against MDCK cells after 48 hrs by neutral red uptake assay | Canis lupus familiaris | 21 | ALA4266060 | cell-based format | Scientific Literature | |
9. | ALA4270388 | A | Half life in mouse liver microsomes at 1 uM in presence of NADPH generating system by LC-MS/MS analysis | Mus musculus | 20 | ALA4266060 | microsome format | Scientific Literature | |
10. | ALA4270389 | A | Intrinsic clearance in mouse liver microsomes at 1 uM in presence of NADPH generating system by LC-MS/MS analysis | Mus musculus | 20 | ALA4266060 | microsome format | Scientific Literature | |
11. | ALA4270412 | A | Half life in mouse liver microsomes at 0.5 uM | Mus musculus | 6 | ALA4266060 | microsome format | Scientific Literature | |
12. | ALA4270413 | A | Intrinsic clearance in mouse liver microsomes at 0.5 uM | Mus musculus | 6 | ALA4266060 | microsome format | Scientific Literature |