# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3420060 | B | Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 8 | ALA3414500 | cell membrane format | Scientific Literature | |
2. | ALA3420061 | B | Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode voltage clamp assay | Influenza A virus (A/udorn/1972(H3N2)) | 7 | ALA3414500 | cell membrane format | Scientific Literature | |
3. | ALA3420062 | B | Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 S31N mutant channel expressed in Xenopus oocyte plasma membranes at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 8 | ALA3414500 | cell membrane format | Scientific Literature | |
4. | ALA3420248 | B | Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes at 100 uM after 2 mins by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 8 | ALA3414500 | cell membrane format | Scientific Literature | |
5. | ALA3420249 | B | Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode voltage clamp assay | Influenza A virus (A/udorn/1972(H3N2)) | 7 | ALA3414500 | cell membrane format | Scientific Literature | |
6. | ALA3420251 | F | Antiviral activity against Influenza A virus (A/PR/8/34(H1N1)) infected in MDCK cells assessed as reduction of virus-induced cytopathic effect after 72 hrs by microscopic analysis | Influenza A virus | 8 | ALA3414500 | organism-based format | Scientific Literature | |
7. | ALA3420252 | F | Antiviral activity against Influenza A virus (A/PR/8/34(H1N1)) infected in MDCK cells assessed as cell viability after 72 hrs by MTS assay | Influenza A virus | 8 | ALA3414500 | organism-based format | Scientific Literature | |
8. | ALA3420253 | F | Antiviral activity against Influenza A virus (A/HK/7/87(H3N2)) infected in MDCK cells assessed as reduction of virus-induced cytopathic effect after 72 hrs by microscopic analysis | Influenza A virus (A/Hong Kong/7/1987(H3N2)) | 8 | ALA3414500 | cell-based format | Scientific Literature | |
9. | ALA3420254 | F | Antiviral activity against Influenza A virus (A/HK/7/87(H3N2)) infected in MDCK cells assessed as cell viability after 72 hrs by MTS assay | Influenza A virus (A/Hong Kong/7/1987(H3N2)) | 8 | ALA3414500 | cell-based format | Scientific Literature | |
10. | ALA3420255 | F | Antiviral activity against Influenza A virus (A/HK/7/87(H3N2)) infected in MDCK cells assessed as virus plaque reduction preincubated for 1 hr followed by compound wash out and incubated for 72 hrs by crystal violet staining | Influenza A virus (A/Hong Kong/7/1987(H3N2)) | 8 | ALA3414500 | cell-based format | Scientific Literature | |
11. | ALA3420256 | F | Antiviral activity against Influenza A virus (A/HK/7/87(H3N2)) infected in MDCK cells assessed as 2-log10 reduction in virus yield after 24 hrs by RT-qPCR analysis | Influenza A virus (A/Hong Kong/7/1987(H3N2)) | 8 | ALA3414500 | cell-based format | Scientific Literature | |
12. | ALA3420257 | A | Cytotoxicity against MDCK cells assessed as cell viability after 72 hrs by MTS assay | Canis lupus familiaris | 6 | ALA3414500 | cell-based format | Scientific Literature | |
13. | ALA3420258 | A | Cytotoxicity against MDCK cells assessed as alternations in cell morphology after 72 hrs | Canis lupus familiaris | 6 | ALA3414500 | cell-based format | Scientific Literature | |
14. | ALA3420259 | F | Antiviral activity against Influenza B virus (B/HK/5/72) infected in MDCK cells assessed as reduction of virus-induced cytopathic effect after 72 hrs by microscopic analysis | Influenza B virus | 6 | ALA3414500 | cell-based format | Scientific Literature |