| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3420628 | B | Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-free assay | Homo sapiens | 49 | assay format | Scientific Literature | ||
| 2. | ALA3420629 | B | Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed by stimulation with A23187 for 10 mins by RP-HPLC based cell based assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
| 3. | ALA3420630 | B | Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as remaining activity by measuring lipoxygenase products formation at 10 uM pre-incubated for 15 mins followed by stimulation with A23187 for 10 mins by RP-HPLC based cell based assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA3420867 | B | Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pre-incubated for 15 mins followed by stimulation with A23187 for 10 mins by RP-HPLC based cell based assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
| 5. | ALA3420868 | B | Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as remaining activity by measuring lipoxygenase products formation at 10 uM in presence of arachidonic acid pre-incubated for 15 mins followed by stimulation with A23187 for 10 mins by RP-HPLC based cell based assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 6. | ALA3420871 | B | Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using PGH2 substrate by RP-HPLC method | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 7. | ALA3420872 | B | Inhibition of 15-LOX-1 in human blood PMNL assessed as remaining activity by measuring 15-HETE synthesis at 10 uM | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 8. | ALA3420874 | B | Inhibition of 12-LOX in human blood PMNL assessed as remaining activity by measuring 12-HETE synthesis at 10 uM | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 9. | ALA3420875 | B | Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as assessed as remaining PGE2 synthase activity at 10 uM after 15 mins using PGH2 substrate by RP-HPLC method | Homo sapiens | 32 | cell-based format | Scientific Literature |
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