# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3418428 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 1.25 uM after 5 days by MTT dye reduction assay | Brugia malayi | 6 | ALA3414470 | organism-based format | Scientific Literature | |
2. | ALA3418429 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 0.625 uM after 5 days by MTT dye reduction assay | Brugia malayi | 6 | ALA3414470 | organism-based format | Scientific Literature | |
3. | ALA3418430 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 0.312 uM after 5 days by MTT dye reduction assay | Brugia malayi | 6 | ALA3414470 | organism-based format | Scientific Literature | |
4. | ALA3418432 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 0.156 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
5. | ALA3418433 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 0.078 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
6. | ALA3418434 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 0.039 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
7. | ALA3418435 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility at 0.019 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
8. | ALA3419286 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 1.25 uM after 5 days by MTT dye reduction assay | Brugia malayi | 6 | ALA3414470 | organism-based format | Scientific Literature | |
9. | ALA3419287 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 0.625 uM after 5 days by MTT dye reduction assay | Brugia malayi | 6 | ALA3414470 | organism-based format | Scientific Literature | |
10. | ALA3419288 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 0.312 uM after 5 days by MTT dye reduction assay | Brugia malayi | 6 | ALA3414470 | organism-based format | Scientific Literature | |
11. | ALA3419290 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 0.156 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
12. | ALA3419291 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 0.078 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
13. | ALA3419292 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 0.039 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
14. | ALA3419293 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility at 0.019 uM after 5 days by MTT dye reduction assay | Brugia malayi | 2 | ALA3414470 | organism-based format | Scientific Literature | |
15. | ALA3419299 | Functional | Antifilarial activity against Brugia malayi adult worm assessed as reduction in motility after 5 days by MTT dye reduction assay | Brugia malayi | 12 | ALA3414470 | organism-based format | Scientific Literature | |
16. | ALA3419300 | Functional | Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Brugia malayi adult worm | 12 | ALA3414470 | cell-based format | Scientific Literature | ||
17. | ALA3419301 | Functional | Antifilarial activity against Brugia malayi microfilaria assessed as reduction in motility after 5 days by MTT dye reduction assay | Brugia malayi | 12 | ALA3414470 | organism-based format | Scientific Literature | |
18. | ALA3419302 | Functional | Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Brugia malayi microfilaria | 12 | ALA3414470 | cell-based format | Scientific Literature | ||
19. | ALA3419303 | ADME | Cytotoxicity against African green monkey Vero cells after 72 hrs by resazurin dye-based fluorescence assay | Chlorocebus sabaeus | 12 | ALA3414470 | cell-based format | Scientific Literature | |
20. | ALA3419304 | Functional | Antifilarial activity against Brugia malayi adult worm infected in jird model assessed as adulticidal activity at 100 mg/kg, sc after 5 days measured till day 45 relative to control | Brugia malayi | 7 | ALA3414470 | organism-based format | Scientific Literature |