# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3418219 | B | Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 41 | ALA3414429 | cell-based format | Scientific Literature | |
2. | ALA3418221 | B | Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 60 | ALA3414429 | cell-based format | Scientific Literature | |
3. | ALA3419982 | B | Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 68 | ALA3414429 | cell-based format | Scientific Literature | |
4. | ALA3419983 | B | Selectivity ratio of IC50 for human recombinant ERAP1 to IC50 for human recombinant ERAP2 | Homo sapiens | 1 | ALA3414429 | assay format | Scientific Literature | |
5. | ALA3419985 | B | Inhibition of ERAP1 in mouse RAW264.7 cells assessed as reduction in interferon-gamma/LPS-induced phagocytosis after 24 hrs by fluorescent latex beads internalization assay | Mus musculus | 4 | ALA3414429 | cell-based format | Scientific Literature | |
6. | ALA3879755 | B | Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected insect cells using L-arginine-7-amido-4-methylcoumarine as substrate by spectrofluorimetric assay | Homo sapiens | 3 | ALA3877337 | cell-based format | Scientific Literature |