# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3418219 | B | Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 41 | ALA3414429 | cell-based format | Scientific Literature | |
2. | ALA3418221 | B | Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 60 | ALA3414429 | cell-based format | Scientific Literature | |
3. | ALA3419982 | B | Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 68 | ALA3414429 | cell-based format | Scientific Literature | |
4. | ALA3829450 | B | Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysis | Homo sapiens | 2 | ALA3826883 | single protein format | Scientific Literature | |
5. | ALA3829451 | B | Inhibition of recombinant human ERAP2 using R-AMC as substrate measured for 15 to 30 mins by microplate fluorescence reader method | Homo sapiens | 2 | ALA3826883 | single protein format | Scientific Literature | |
6. | ALA3879755 | B | Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected insect cells using L-arginine-7-amido-4-methylcoumarine as substrate by spectrofluorimetric assay | Homo sapiens | 3 | ALA3877337 | cell-based format | Scientific Literature | |
7. | ALA4024805 | B | Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assay | Homo sapiens | 31 | ALA4024701 | cell-based format | Scientific Literature | |
8. | ALA4024806 | B | Inhibition of ERAP2 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assay | Homo sapiens | 31 | ALA4024701 | cell-based format | Scientific Literature | |
9. | ALA4024807 | B | Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assay | Homo sapiens | 31 | ALA4024701 | cell-based format | Scientific Literature | |
10. | ALA4427448 | B | Inhibition of human recombinant ERAP1 using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence microplate reader method | Homo sapiens | 1 | ALA4425167 | single protein format | Scientific Literature | |
11. | ALA4820030 | B | Inhibition of human ERAP2 | Homo sapiens | 3 | ALA4819009 | single protein format | Scientific Literature | |
12. | ALA4820031 | B | Inhibition of human ERAP1 | Homo sapiens | 3 | ALA4819009 | single protein format | Scientific Literature | |
13. | ALA4822041 | B | Inhibition of APN (unknown origin) using A-AMC as substrate | Homo sapiens | 6 | ALA4819094 | single protein format | Scientific Literature | |
14. | ALA4822042 | B | Inhibition of ERAP1 (unknown origin) using L-AMC as substrate | Homo sapiens | 6 | ALA4819094 | single protein format | Scientific Literature | |
15. | ALA4822043 | B | Inhibition of ERAP2 (unknown origin) using R-AMC as substrate | Homo sapiens | 6 | ALA4819094 | single protein format | Scientific Literature | |
16. | ALA4822044 | A | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 6 | ALA4819094 | cell-based format | Scientific Literature | |
17. | ALA4822046 | B | Inhibition of recombinant human ERAP1 using L-AMC as substrate incubated for 5 to 10 mins by fluorescence based assay | Homo sapiens | 1 | ALA4819094 | single protein format | Scientific Literature | |
18. | ALA4822047 | B | Inhibition of recombinant human ERAP2 using R-AMC as substrate incubated for 5 to 10 mins by fluorescence based assay | Homo sapiens | 1 | ALA4819094 | single protein format | Scientific Literature | |
19. | ALA4824855 | B | Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by flourescence assay | Homo sapiens | 20 | ALA4823288 | single protein format | Scientific Literature | |
20. | ALA4824866 | B | Inhibition of APN (unknown origin) using Ala-AMC as substrate | Homo sapiens | 18 | ALA4823288 | single protein format | Scientific Literature |