| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3418578 | F | Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay | Homo sapiens | 13 | ALA3414542 | cell-based format | Scientific Literature | |
| 2. | ALA3418579 | F | Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay | Homo sapiens | 13 | ALA3414542 | cell-based format | Scientific Literature | |
| 3. | ALA3418580 | F | Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay | Homo sapiens | 13 | ALA3414542 | cell-based format | Scientific Literature | |
| 4. | ALA3418581 | F | Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay | Homo sapiens | 13 | ALA3414542 | cell-based format | Scientific Literature | |
| 5. | ALA3418582 | B | Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA | Homo sapiens | 11 | ALA3414542 | single protein format | Scientific Literature | |
| 6. | ALA3418583 | P | Octanol-water partition coefficient, log P of the compound by shake-flask method | 10 | ALA3414542 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA3861286 | B | Inhibition of His-tagged full length Hsp90/GST-tagged Cdc37 middle domain (unknown origin) interaction at 50 uM after 1 hr by TR-FRET assay relative to control | Homo sapiens | 24 | ALA3860070 | assay format | Scientific Literature | |
| 8. | ALA3861288 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 24 | ALA3860070 | cell-based format | Scientific Literature | |
| 9. | ALA3861289 | F | Antiproliferative activity against human PANC1 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 24 | ALA3860070 | cell-based format | Scientific Literature | |
| 10. | ALA3861290 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 24 | ALA3860070 | cell-based format | Scientific Literature | |
| 11. | ALA4396411 | B | Binding affinity to recombinant human N-terminal His-tagged Nur77 LBD (367 to 598 residues) expressed in Escherichia coli BL21(DE3) incubated for 30 secs by fluorescence quenching assay | Homo sapiens | 25 | ALA4393721 | assay format | Scientific Literature | |
| 12. | ALA4396413 | F | Antiinflammatory activity in human HepG2 cells assessed as inhibition of TNFalpha-induced IkappaBalpha degradation at 2 uM pretreated for 1 hr followed by TNFalpha addition and measured after 30 mins by Western blot analysis | Homo sapiens | 25 | ALA4393721 | cell-based format | Scientific Literature | |
| 13. | ALA4669986 | A | Cytotoxicity against BALB/c mouse T cell assessed as reduction in cell viability after 48 hrs by CCK8 assay | Mus musculus | 44 | ALA4665764 | tissue-based format | Scientific Literature | |
| 14. | ALA4669987 | F | Antiproliferative activity against Con A-induced BALB/c mouse T cell after 48 hrs by CCK8 assay | Mus musculus | 44 | ALA4665764 | tissue-based format | Scientific Literature | |
| 15. | ALA4669988 | U | Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse T cell to IC50 for antiproliferative activity against Con A-induced BALB/c mouse T cell | Mus musculus | 44 | ALA4665764 | tissue-based format | Scientific Literature | |
| 16. | ALA4669989 | F | Induction of apoptosis in BALB/c mouse T cell assessed as increase in Bax at >=1 uM by Western blot analysis | Mus musculus | 1 | ALA4665764 | tissue-based format | Scientific Literature | |
| 17. | ALA4669990 | F | Induction of apoptosis in BALB/c mouse T cell assessed as increase in Bcl2 at >=1 uM by Western blot analysis | Mus musculus | 1 | ALA4665764 | tissue-based format | Scientific Literature | |
| 18. | ALA4669991 | F | Induction of mitochondrial membrane disruption in BALB/c mouse T cell assessed as increase in cytochrome c release from mitochondria to cytosol at >=1 uM by Western blot analysis | Mus musculus | 1 | ALA4665764 | mitochondrion format | Scientific Literature | |
| 19. | ALA4669992 | F | Induction of apoptosis in BALB/c mouse T cell assessed as assessed as increase in caspase 3 >=1 uM | Mus musculus | 1 | ALA4665764 | tissue-based format | Scientific Literature | |
| 20. | ALA4669993 | F | Induction of apoptosis in BALB/c mouse T cell assessed as assessed as increase in caspase 9 >=1 uM | Mus musculus | 1 | ALA4665764 | tissue-based format | Scientific Literature |
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