# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3417877 | B | Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
2. | ALA3417878 | B | Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
3. | ALA3417879 | B | Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
4. | ALA3417880 | F | Induction of apoptosis in wild-type MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
5. | ALA3417881 | F | Induction of apoptosis in Bcl2-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
6. | ALA3417882 | F | Induction of apoptosis in Bad-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
7. | ALA3417883 | F | Induction of apoptosis in Bid-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
8. | ALA3417884 | F | Induction of apoptosis in Bak-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
9. | ALA3417885 | F | Induction of apoptosis in Bax-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA3420567 | F | Induction of apoptosis in Bax/Bak-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
11. | ALA3420576 | B | Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by spectrophotometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
13. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
14. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
15. | ALA4808149 | B | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 | ||
16. | ALA4808150 | B | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 |